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Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae.
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2
Macrolide efflux in Streptococcus pneumoniae is mediated by a dual efflux pump (mel and mef) and is erythromycin inducible.
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Macrolide Resistance in .
Front Cell Infect Microbiol. 2016 Sep 21;6:98. doi: 10.3389/fcimb.2016.00098. eCollection 2016.
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Induction of efflux-mediated macrolide resistance in Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2011 Jul;55(7):3413-22. doi: 10.1128/AAC.00060-11. Epub 2011 May 2.
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Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco.
Infect Genet Evol. 2016 Jun;40:200-204. doi: 10.1016/j.meegid.2016.03.003. Epub 2016 Mar 4.
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Inducible Mega-Mediated Macrolide Resistance Confers Heteroresistance in Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2023 Mar 16;67(3):e0131922. doi: 10.1128/aac.01319-22. Epub 2023 Feb 27.

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Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation.
Antibiotics (Basel). 2024 Dec 24;14(1):1. doi: 10.3390/antibiotics14010001.
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Molecular Mechanisms of Bacterial Resistance to Antimicrobial Peptides in the Modern Era: An Updated Review.
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A Review of the Resistance Mechanisms for -Lactams, Macrolides and Fluoroquinolones among .
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Inducible Mega-Mediated Macrolide Resistance Confers Heteroresistance in Streptococcus pneumoniae.
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Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health.
Sci Total Environ. 2023 Feb 20;860:160461. doi: 10.1016/j.scitotenv.2022.160461. Epub 2022 Nov 23.
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Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance.
R Soc Open Sci. 2022 Jan 26;9(1):211583. doi: 10.1098/rsos.211583. eCollection 2022 Jan.
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The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent.
Antibiotics (Basel). 2021 May 29;10(6):650. doi: 10.3390/antibiotics10060650.
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Comparative population genomic analyses of transporters within the Asgard archaeal superphylum.
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Molecular engineering of antimicrobial peptides: microbial targets, peptide motifs and translation opportunities.
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本文引用的文献

2
Increase in pneumococcus macrolide resistance, United States.
Emerg Infect Dis. 2009 Aug;15(8):1260-4. doi: 10.3201/eid1508.081187.
3
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense.
Trends Immunol. 2009 Mar;30(3):131-41. doi: 10.1016/j.it.2008.12.003. Epub 2009 Feb 13.
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Induction of group A Streptococcus virulence by a human antimicrobial peptide.
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16755-60. doi: 10.1073/pnas.0803815105. Epub 2008 Oct 20.
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A case series of macrolide treatment failures in community acquired pneumonia.
J Chemother. 2007 Oct;19(5):536-45. doi: 10.1179/joc.2007.19.5.536.
7
A new integrative reporter plasmid for Streptococcus pneumoniae.
FEMS Microbiol Lett. 2007 Mar;268(2):217-24. doi: 10.1111/j.1574-6968.2006.00584.x.
9
Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps.
Cell Microbiol. 2007 May;9(5):1162-71. doi: 10.1111/j.1462-5822.2006.00857.x. Epub 2007 Jan 9.

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