Boekhoff I, Breer H
University Stuttgart-Hohenheim, Department of Zoophysiology, Garbenstrasse 30, 7000 Stuttgart 70, F.R.G.
Neurochem Int. 1990;17(4):553-7. doi: 10.1016/0197-0186(90)90043-s.
Using ciliary preparations from rat olfactory epithelia, representative compounds of different odorant classes were assayed for the capability of stimulating the formation of second messengers in a subsecond time range. Fruity, floral and minty odors were found to induce a transient accumulation of cyclic adenosine monophosphate, whereas the herbaceous and putrid compounds under test caused a rise in inositol trisphosphate concentration.
利用大鼠嗅觉上皮的纤毛制剂,对不同气味类别中的代表性化合物进行了检测,以评估它们在亚秒时间范围内刺激第二信使形成的能力。结果发现,水果味、花香和薄荷味的气味会诱导环磷酸腺苷的短暂积累,而受试的草本和腐臭味化合物则会导致肌醇三磷酸浓度升高。