Siebenmann R, Egloff L, Hirzel H O, Rothlin M, Studer M, Tartini R
HerzZentrum Hirslanden, Zürich.
Helv Chir Acta. 1991 Jan;57(4):591-4.
Incidence, risk and results of emergency coronary bypass surgery after failed percutaneous transluminal coronary angioplasty (PTCA) have been analyzed in a retrospective study. Failed PTCA has been defined as visible pathology (dissection, occlusion) of the dilated vessel associated with acute chest pain and ECG changes. From 3-1-1987 to 11-30-1990, 23 patients of 433 (5%) underwent emergency surgery for failed PTCA (19 male, 4 female, mean age 55 +/- 8 years). PTCA was performed in 16 cases of one-vessel-disease, 3 cases of two-vessel-disease and 4 cases of three-vessel-disease. All had an ejection fraction beyond 40%. 19 patients remained in stable hemodynamic condition. In average 2.1 vessels have been bypassed; in 13 cases the internal mammary artery (IMA) has been used, in 10 cases the saphenous vein (VSM) only. No early nor late death occurred. The perioperative infarction rate is 30%. Comparing the group with IMA and the group with VSM only, no difference could be found regarding the number of unstable hemodynamics, the use of catecholamines nor the perioperative infarction rate. After a mean follow-up period of 14.3 months, 21 patients are in NYHA class I, 2 in NYHA class II. Emergency coronary bypass surgery can be performed with low risk and favorable results, if the operation is timed without delay after the onset of acute chest pain and ECG changes in failed PTCA. The infarction rate is remarkably higher than in elective coronary surgery. The use of the IMA seems to be no additional risk factor.
一项回顾性研究分析了经皮腔内冠状动脉成形术(PTCA)失败后急诊冠状动脉搭桥手术的发生率、风险及结果。PTCA失败被定义为扩张血管出现可见病变(夹层、闭塞)并伴有急性胸痛和心电图改变。从1987年1月3日至1990年11月30日,433例患者中有23例(5%)因PTCA失败接受了急诊手术(男性19例,女性4例,平均年龄55±8岁)。PTCA用于单支血管病变16例、双支血管病变3例和三支血管病变4例。所有患者射血分数均超过40%。19例患者血流动力学保持稳定。平均搭桥2.1支血管;13例使用了乳内动脉(IMA),10例仅使用了大隐静脉(VSM)。无早期或晚期死亡发生。围手术期梗死率为30%。比较IMA组和仅使用VSM组,在不稳定血流动力学的数量、儿茶酚胺的使用及围手术期梗死率方面未发现差异。平均随访14.3个月后,21例患者心功能为纽约心脏协会(NYHA)I级,2例为NYHA II级。如果在PTCA失败后急性胸痛和心电图改变出现后及时进行手术,急诊冠状动脉搭桥手术可在低风险下取得良好效果。梗死率明显高于择期冠状动脉手术。使用IMA似乎不是额外的风险因素。