Division of Medical Genetics, University of California, San Francisco, CA 94143-0794, USA.
Prenat Diagn. 2010 Jun;30(6):575-81. doi: 10.1002/pd.2529.
This study assessed decisional conflict about invasive prenatal testing among women pregnant after infertility.
We surveyed 180 pregnant women with a history of infertility using a mixed methods cross-sectional design. Difficulty in deciding whether to have prenatal testing was measured using the Decisional Conflict Scale.
A minority of women (31%) chose to have invasive prenatal testing. Most participants (72%) reported low decisional conflict (score < 25; mean = 22.1; standard deviation = 23.2; range: 0-100). Half (53%) of the participants said that infertility made the testing decision easier. Qualitative data suggest that infertility makes the decision easier by clarifying relevant values and priorities. Most infertility characteristics studied were not significantly associated with decisional conflict. Variables associated with higher decisional conflict included infertility distress due to rejection of a childfree lifestyle, disagreement with others about testing, and choosing to have invasive testing after having had treatment for infertility.
For some women, infertility may make the invasive prenatal testing decision easier. Women with the greatest need for decisional support were those who have had treatment and choose invasive testing, who disagree with others about their testing choice, or who are particularly distressed about being childless.
本研究评估了不孕后妊娠女性对有创性产前检测的决策冲突。
我们采用混合方法的横断面设计,对 180 名有不孕史的孕妇进行了调查。使用决策冲突量表来衡量是否进行产前检测的决策困难程度。
少数女性(31%)选择进行有创性产前检测。大多数参与者(72%)报告的决策冲突较低(评分<25;平均值=22.1;标准差=23.2;范围:0-100)。有一半(53%)的参与者表示,不孕使检测决策变得更容易。定性数据表明,不孕通过明确相关价值观和优先事项使决策变得更容易。研究中大多数不孕特征与决策冲突无显著关联。与更高决策冲突相关的变量包括因拒绝无子女生活方式而产生的不孕困扰、与他人对检测的意见不一致,以及在接受不孕治疗后选择进行有创性检测。
对于一些女性来说,不孕可能会使有创性产前检测的决策变得更容易。最需要决策支持的女性是那些接受过治疗并选择进行有创性检测、与他人对检测选择意见不一致,或特别因不能生育而感到困扰的女性。