Senturk Senem, Guzel Ebru, Bayrak Aylin Hasanefendioglu, Bukte Yasar, Guzel Aslan
Department of Radiology, Medical School, Dicle University, Diyarbakir, Turkey.
Pediatr Neurosurg. 2010;46(1):54-7. doi: 10.1159/000315004. Epub 2010 May 27.
Factor X deficiency is a rare coagulation defect that can result in several hemorrhagic manifestations including central nervous system hematomas in infants and children. In this case report, we present computed tomography (CT) and magnetic resonance (MR) imaging findings of bilateral chronic subdural hematomas due to factor X deficiency. Cranial CT and MR imaging in a hypoactive 7-month-old male infant with right hemiparesis revealed bilateral chronic subdural hematomas at different stages. Laboratory findings showed a severe factor X deficiency, with a level of 0.7%. After fresh frozen plasma replacement, the patient was operated and the large hematoma on the left side evacuated. The patient recovered uneventfully and remained asymptomatic during the 1-year follow-up.
因子X缺乏是一种罕见的凝血缺陷,可导致多种出血表现,包括婴幼儿中枢神经系统血肿。在本病例报告中,我们展示了因因子X缺乏导致的双侧慢性硬膜下血肿的计算机断层扫描(CT)和磁共振(MR)成像结果。一名活动减少、右半身轻瘫的7个月大男婴的头颅CT和MR成像显示双侧处于不同阶段的慢性硬膜下血肿。实验室检查结果显示严重的因子X缺乏,水平为0.7%。在输注新鲜冰冻血浆后,患者接受了手术,左侧的大血肿被清除。患者恢复顺利,在1年的随访期间无症状。