Chengdu University of Traditional Chinese Medicine, China.
Chin J Integr Med. 2010 Oct;16(5):472-9. doi: 10.1007/s11655-010-9995-0. Epub 2010 Jun 10.
In this paper we investigated the mechanisms of Baihu Decoction ((白虎汤, BH) and Baihu with Radix Ginseng (BHG) in treating systemic inflammatory response syndrome (SIRS) and sepsis in humans and animals. By reviewing published data on the effects of BH and BHG and the control of blood glucose in treating SIRS and sepsis, we found that (1) BH and BHG were beneficial in the treatment of SIRS and sepsis in humans and animals; (2) BH and BHG also had great effect in lowering blood glucose level; and (3) the tight control of blood glucose during critical illness substantially improved the outcome. Considering these data together, we hypothesize that one of the major mechanisms of BH and BHG in treating SIRS and sepsis is to lower the blood glucose level. The findings also suggest that the application of BH and BHG can extend to many acute illnesses and injuries, which commonly cause hyperglycemia.
在本文中,我们研究了白虎汤(BH)和白虎加人参汤(BHG)治疗人类和动物全身炎症反应综合征(SIRS)和脓毒症的机制。通过回顾已发表的关于 BH 和 BHG 对 SIRS 和脓毒症的影响以及对血糖控制的研究数据,我们发现:(1)BH 和 BHG 对人类和动物的 SIRS 和脓毒症治疗有益;(2)BH 和 BHG 也能有效降低血糖水平;(3)在危重病期间严格控制血糖可显著改善预后。综合这些数据,我们推测 BH 和 BHG 治疗 SIRS 和脓毒症的主要机制之一是降低血糖水平。研究结果还表明,BH 和 BHG 的应用可以扩展到许多急性疾病和损伤,这些疾病和损伤通常会导致高血糖。