Kartal Kosuyolu Heart Education and Research Hospital, Department of Cardiology, Istanbul, Turkey.
Clin Cardiol. 2010 Jun;33(6):E114-5. doi: 10.1002/clc.20647.
Sertraline is a selective serotonin reuptake inhibitor with established safety for the treatment of depression. Among the common adverse effects associated with sertraline are nausea, insomnia, diarrhea, somnolence, and dizziness. Cardiac arrest had not been reported in the literature, although tachycardia was frequently seen. In this case report, a patient was presented who had adverse reactions such as nausea, dizziness, insomnia under citalopram treatment, and after his drug was changed to sertraline, developed sinus arrest on the fourth day of treatment.
舍曲林是一种选择性 5-羟色胺再摄取抑制剂,已被证实可安全用于治疗抑郁症。舍曲林常见的不良反应包括恶心、失眠、腹泻、嗜睡和头晕。尽管常可见到心动过速,但文献中并未报道过心脏骤停。在本病例报告中,介绍了一位患者,他在接受西酞普兰治疗时出现恶心、头晕、失眠等不良反应,换用舍曲林治疗后第四天出现窦性停搏。