Health Economist, HERA Consulting Australia, Balmain, NSW, Australia.
Value Health. 2010 Sep-Oct;13(6):750-60. doi: 10.1111/j.1524-4733.2010.00759.x. Epub 2010 Jun 17.
The Monitor Practice Program demonstrated that regular monitoring and noninvasive management of dental caries is effective in reducing the incremental DMFT (decayed, missing, and filled teeth) in patients, within the construct of a 3-year randomized clinical trial. This analysis evaluates the long-term cost-effectiveness of the preventive approach underpinning the Caries Management System, used in the general practice setting and modeled to the Australian population.
An individual patient-simulation Markov model was developed to compare the long-term costs and outcomes of the Caries Management System versus standard dental care in a hypothetical sample representative of the Australian population. Eight Markov submodels were developed, representing eight molar teeth (excluding wisdom teeth), each consisting of 11 health states simulating the incidence and progression of dental caries, and future interventions such as fillings and crowns. Transition probabilities and costs assigned to health states were based on claims data from the second largest private health insurer in Australia. The economic evaluation was performed from the Australian private dental practitioner perspective. The incremental cost per DMFT avoided was calculated at three time points: 2 years, 3 years, and lifetime. Univariate sensitivity analysis was conducted to test the robustness of the results.
The incremental cost per DMFT avoided at 2 years, 3 years, and lifetime was estimated to be $1287.07, $1148.91, and $1795.06, respectively.
The analysis suggests that the Caries Management System is most cost-effective in patients with a high risk of dental caries.
监测实践计划表明,在一项为期 3 年的随机临床试验中,定期监测和无创性管理龋齿对于减少患者的增量 DMFT(龋齿、缺失和填充的牙齿)是有效的。本分析评估了在普通实践环境中使用的龋齿管理系统背后的预防性方法的长期成本效益,并针对澳大利亚人群进行了建模。
开发了一个个体患者模拟 Markov 模型,以比较龋齿管理系统与标准牙科护理在代表澳大利亚人群的假设样本中的长期成本和结果。开发了 8 个 Markov 子模型,代表 8 颗磨牙(不包括智齿),每个子模型由 11 个健康状态组成,模拟龋齿的发生和进展,以及未来的干预措施,如补牙和牙冠。健康状态的转移概率和成本是基于澳大利亚第二大私人健康保险公司的索赔数据确定的。经济评估是从澳大利亚私人牙医的角度进行的。在三个时间点(2 年、3 年和终生)计算了每避免一个 DMFT 的增量成本。进行了单变量敏感性分析以测试结果的稳健性。
估计在 2 年、3 年和终生避免每一个 DMFT 的增量成本分别为 1287.07 美元、1148.91 美元和 1795.06 美元。
分析表明,龋齿管理系统在龋齿风险高的患者中最具成本效益。