Suppr超能文献

系统药理学培训:西奈山医学院药理学和系统生物学博士前项目。

Training in systems pharmacology: predoctoral program in pharmacology and systems biology at Mount Sinai School of Medicine.

机构信息

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine and Systems Biology Center, New York, New York, USA.

出版信息

Clin Pharmacol Ther. 2010 Jul;88(1):19-22. doi: 10.1038/clpt.2010.41.

Abstract

Our recently developed predoctoral training program in pharmacology and systems biology prepares students to become experts in systems-level models of disease that identify therapeutic targets and predict adverse effects or new uses of existing therapeutics. Multiple computational modeling modes are introduced throughout a curriculum that integrates basic cell and molecular sciences with the physiology and pathophysiology of disease states. Problem-based learning exercises enable students from different experimental and computational backgrounds to design experiments and interpret data quantitatively.

摘要

我们最近开设的药理学和系统生物学博士前培训计划,旨在培养学生成为疾病系统水平模型方面的专家,以确定治疗靶点,并预测现有治疗方法的不良反应或新用途。整个课程整合了基础细胞和分子科学、疾病生理和病理生理学,引入了多种计算建模模式。基于问题的学习练习使来自不同实验和计算背景的学生能够设计实验并进行定量数据分析。

相似文献

2
Clinical pharmacology teaching, training and career development.
Clin Pharmacol Ther. 1986 Apr;39(4):466-70. doi: 10.1038/clpt.1986.80.
5
Emergency medicine at the Mount Sinai School of Medicine.
Mt Sinai J Med. 1999 Oct-Nov;66(5-6):303-9.
6
A model of pharmacology education: the experience of Istanbul Medical Faculty.
J Clin Pharmacol. 2003 Mar;43(3):237-42. doi: 10.1177/0091270003251116.
8
Teaching of clinical pharmacology and therapeutics in UK medical schools: current status in 2009.
Br J Clin Pharmacol. 2010 Jul;70(1):143-8. doi: 10.1111/j.1365-2125.2010.03665.x.
10
A curricular divide: basic pharmacology vs. clinical pharmacology.
Clin Pharmacol Ther. 2011 Jan;89(1):24-6. doi: 10.1038/clpt.2010.75.

引用本文的文献

1
Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape.
CPT Pharmacometrics Syst Pharmacol. 2018 Mar;7(3):135-146. doi: 10.1002/psp4.12282. Epub 2018 Feb 1.
2
NIH Support for the Emergence of Quantitative and Systems Pharmacology.
CPT Pharmacometrics Syst Pharmacol. 2013 Apr 10;2(4):e37. doi: 10.1038/psp.2013.13.
3
Systems biology--biomedical modeling.
Sci Signal. 2011 Sep 6;4(190):tr2. doi: 10.1126/scisignal.2001989.
4
The grand challenge for integrative and regenerative pharmacology.
Front Pharmacol. 2011 Feb 14;2:5. doi: 10.3389/fphar.2011.00005. eCollection 2011.

本文引用的文献

1
Network analyses in systems pharmacology.
Bioinformatics. 2009 Oct 1;25(19):2466-72. doi: 10.1093/bioinformatics/btp465. Epub 2009 Jul 30.
2
Systems pharmacology and genome medicine: a future perspective.
Genome Med. 2009 Jan 22;1(1):11. doi: 10.1186/gm11.
3
Inquiry learning. Integrating content detail and critical reasoning by peer review.
Science. 2008 Feb 29;319(5867):1189-90. doi: 10.1126/science.1149875.
5
What IS training in the Pharmacological Sciences?
Mol Interv. 2002 Sep;2(5):270-5. doi: 10.1124/mi.2.5.270.
6
Introductory science and mathematics education for 21st-Century biologists.
Science. 2004 Feb 6;303(5659):788-90. doi: 10.1126/science.1095480.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验