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用于宽颈和梭形颅内动脉瘤血管内治疗的Leo支架

Leo stent for endovascular treatment of broad-necked and fusiform intracranial aneurysms.

作者信息

Juszkat R, Nowak S, Smól S, Kociemba W, Blok T, Zarzecka A

机构信息

Department of Neuroradiology, Poznan University of Medical Sciences, Poznaf, Poland - Department of Neurosurgery and Neurotraumatology, Poznan University of Medical Sciences, Poznaf, Poland -

出版信息

Interv Neuroradiol. 2007 Sep;13(3):255-69. doi: 10.1177/159101990701300305. Epub 2007 Sep 15.

Abstract

The advent of intracranial stents has widened the indications for endovascular treatment of broad-necked and fusiform aneurysms. Leo stent is a self-expandable, nitinol, braided stent dedicated to intracranial vessels. The aim of this study is to present our experience in endovascular treatment of broad-necked and fusiform intracranial aneurysms using self-expanding, nitinol Leo stents. Between February 2004 and November 2006, 25 broad-necked and three fusiform aneurysms in 28 patients were treated using Leo stents in our centre. There were 18 patients who experienced acute subarachnoid haemorrhage due to aneurysm rupture, two patients who experienced SAH at least 12 months ago and in eight patients aneurysms were found incidentally. Aneurysms were located as follows: internal carotid artery (15), basilar artery (5), basilar tip (3), posterior inferior cerebral artery (2), M1/M2 segment (1), A2 segment (1) and vertebral artery (1). There were no difficulties with stent deployment and delivery. All patients after acute SAH (n=18) underwent stent implantation and coil embolization in one procedure. The remaining patients underwent coil embolization in a staged procedure. Immediate aneurysm occlusion of more than 95% was achieved in all patients who underwent stent placement and coil embolization in one procedure. There were three thromboembolic complications encountered in patients in an acute setting of SAH, preloaded only on acetylsalicylic acid. Use of abciximab led to patency within the stent and parent vessel. However, one of these patients presented rebleeding from the aneurysm during administration of abciximab and died. Application of Leo stents in cases of broadnecked and fusiform intracranial aneurysms is safe and effective with a low complication rate.

摘要

颅内支架的出现拓宽了宽颈和梭形动脉瘤血管内治疗的适应症。Leo支架是一种专门用于颅内血管的自膨胀镍钛合金编织支架。本研究的目的是介绍我们使用自膨胀镍钛合金Leo支架对宽颈和梭形颅内动脉瘤进行血管内治疗的经验。2004年2月至2006年11月期间,我们中心使用Leo支架治疗了28例患者的25个宽颈动脉瘤和3个梭形动脉瘤。18例患者因动脉瘤破裂发生急性蛛网膜下腔出血,2例患者至少在12个月前发生蛛网膜下腔出血,8例患者为偶然发现动脉瘤。动脉瘤的位置如下:颈内动脉(15个)、基底动脉(5个)、基底动脉尖(3个)、大脑后下动脉(2个)、M1/M2段(1个)、A2段(1个)和椎动脉(1个)。支架的展开和输送没有困难。所有急性蛛网膜下腔出血患者(n = 18)均在一次手术中进行了支架植入和弹簧圈栓塞。其余患者分阶段进行弹簧圈栓塞。所有在一次手术中接受支架置入和弹簧圈栓塞的患者均实现了动脉瘤即刻闭塞率超过95%。在急性蛛网膜下腔出血患者中,仅预先使用阿司匹林时出现了3例血栓栓塞并发症。使用阿昔单抗可使支架和母血管保持通畅。然而,其中1例患者在使用阿昔单抗期间动脉瘤再次出血并死亡。在宽颈和梭形颅内动脉瘤病例中应用Leo支架是安全有效的,并发症发生率低。

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