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伴有生殖器累及的延伸型腹膜后坏死性筋膜炎,类似 Fournier 坏疽。

Extended retroperitoneal necrotizing fasciitis with genital involvement, resembling fournier gangrene.

机构信息

Department of Surgery, Okinawa Yaeyama Hospital, Okinawa, Japan .

出版信息

Surg Infect (Larchmt). 2010 Oct;11(5):463-7. doi: 10.1089/sur.2008.101.

Abstract

BACKGROUND

Necrotizing fasciitis is a serious infection that originates in the subcutaneous tissues. Although many reports have been published about necrotizing infections of other anatomical sites, retroperitoneal necrotizing soft tissue infection is a rare entity that has been described in only a few case reports. The etiology and clinical course of retroperitoneal necrotizing fasciitis can be variable and it is often difficult to identify the etiology of the infective process.

CASE REPORT

We report a 58-year-old man with rapidly progressive, gas-producing, necrotizing inflammation in the retroperitoneum, complicated with genital involvement resembling Fournier gangrene. The patient was managed successfully by aggressive drainage, debridement, and sequential laparotomies to track and control the extensive necrosis of the retroperitoneum and perineum, in addition to systemic care to control sepsis. After his general condition stabilized, early rectosigmoid adenocarcinoma was identified and resected curatively. He remained well at follow up, six months after discharge.

RESULTS

In retrospect, the trigger of the disease process was unclear. Although it was believed possibly to be due to the colon lesion, adenocarcinoma of the rectosigmoid colon was identified and the patient was managed successfully.

CONCLUSIONS

Similar to necrotizing infections at other anatomical sites, early diagnosis and timely surgical intervention and systemic antimicrobial therapy are mandatory for treating patients with retroperitoneal necrotizing fasciitis.

摘要

背景

坏死性筋膜炎是一种起源于皮下组织的严重感染。虽然已有许多关于其他解剖部位坏死性感染的报道,但腹膜后坏死性软组织感染是一种罕见的疾病,仅在少数病例报告中有所描述。腹膜后坏死性筋膜炎的病因和临床过程可能有所不同,通常很难确定感染过程的病因。

病例报告

我们报告了一例 58 岁男性,其腹膜后迅速进展、产气、坏死性炎症,伴有类似 Fournier 坏疽的生殖器受累。通过积极引流、清创和连续剖腹手术,以跟踪和控制腹膜后和会阴的广泛坏死,以及进行全身治疗以控制败血症,患者得到了成功的治疗。在一般情况稳定后,早期发现并治愈性切除了直肠乙状结肠腺癌。患者在出院后 6 个月时情况良好。

结果

回顾性分析,疾病过程的触发因素不明确。虽然认为可能与结肠病变有关,但发现并成功治疗了直肠乙状结肠腺癌。

结论

与其他解剖部位的坏死性感染类似,早期诊断和及时的手术干预以及全身抗菌治疗对于治疗腹膜后坏死性筋膜炎患者是必需的。

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