PSSRU, University of Manchester, Oxford Road, Manchester M13 9PL, UK.
J Psychiatr Ment Health Nurs. 2010 Jun;17(5):463-8. doi: 10.1111/j.1365-2850.2009.01546.x.
Concerns have been expressed about the use of antipsychotics with older people, particularly in those who have dementia. Pro re nata (PRN) psychotropic medications including antipsychotics are commonly used to manage disturbed and distressed behaviour. This audit aimed to understand the use of PRN psychotropic medications in older people's inpatient mental health services and the quality of prescriptions and nursing documentation associated with this. A retrospective audit was undertaken on 154 patients on 11 wards in three Mental Health Trusts in the North West of England. A proforma adapted from previous research was used to collect data. Eighty-seven patients were prescribed combinations of 14 psychotropic drugs in 145 different prescriptions as PRN. Seventy-six doses of PRN were administered to 26 patients (range 1-17 doses). The most commonly administered drug was Lorazepam (n = 28, 36.8%). Drugs were most frequently administered during the night (n = 33, 43.4%). The majority of administrations of PRN were not documented (n = 45, 59.2%). PRN appeared to be used differently (smaller doses and less frequently) in this study compared to previous research of those aged under 65. Further work needs to examine the use of the use of PRN psychotropic medicines and the older person, and focus on developing alternative nonpharmacological interventions.
人们对在老年人中使用抗精神病药物表示担忧,尤其是在患有痴呆症的老年人中。包括抗精神病药物在内的按需(PRN)精神药物通常用于治疗紊乱和痛苦的行为。本次审计旨在了解老年人住院精神卫生服务中 PRN 精神药物的使用情况,以及与此相关的处方和护理记录的质量。在英格兰西北部的三个心理健康信托基金的 11 个病房中,对 154 名患者进行了回顾性审计。使用了一种从先前研究中改编的表格来收集数据。在 145 份不同的处方中,有 87 名患者被开具了 14 种精神药物的组合作为 PRN。有 26 名患者(范围为 1-17 次剂量)接受了 76 次 PRN 给药。给予的最常见药物是劳拉西泮(n = 28,36.8%)。药物最常(n = 33,43.4%)在夜间给药。大部分 PRN 给药未记录(n = 45,59.2%)。与之前对 65 岁以下人群的研究相比,本研究中 PRN 的使用方式似乎有所不同(剂量较小且频率较低)。需要进一步研究 PRN 精神药物的使用情况以及老年人,并侧重于开发替代非药物干预措施。