立体视盘摄影的自动容积评估
Automated volumetric evaluation of stereoscopic disc photography.
作者信息
Xu Juan, Ishikawa Hiroshi, Wollstein Gadi, Bilonick Richard A, Kagemann Larry, Craig Jamie E, Mackey David A, Hewitt Alex W, Schuman Joel S
机构信息
UPMC Eye Center, Ophthalmology and Visual Science Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
出版信息
Opt Express. 2010 May 24;18(11):11347-59. doi: 10.1364/OE.18.011347.
PURPOSE
To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements.
METHODS
One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques.
RESULTS
AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods.
CONCLUSION
AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.
目的
开发一种全自动算法（AP），利用传统的立体视盘照片对视盘进行容积测量，并将算法生成的参数与手动摄影测量法（MP）、扫描激光检眼镜（SLO）和光学相干断层扫描（OCT）测量结果进行比较。
方法
分析了122张立体视盘照片（61名受试者）。该算法自动计算视盘面积、视盘边缘面积、视杯面积、视杯/视盘面积比、垂直视杯/视盘比、视盘边缘体积和视杯体积。使用潜在变量测量误差模型评估这四种技术的测量可重复性。
结果
与MP、SLO和OCT方法相比，AP在视盘面积和视杯体积方面具有更好的可重复性，而在视杯/视盘面积比和垂直视杯/视盘比方面具有较差的可重复性。
结论
AP为客观定量评估三维视盘结构提供了一种有用的技术。
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