Van den Driessche Annelies, Van Hul Erik, Ichiche Malika, Verpooten Gert A, Bosmans Jean-Louis
Department of Nephrology-Hypertension, Antwerp University Hospital, Edegem (Antwerpen), Belgium.
J Med Case Rep. 2010 Jun 30;4:199. doi: 10.1186/1752-1947-4-199.
Fibromuscular dysplasia is a non-atherosclerotic, non-inflammatory disease that most commonly affects the renal and internal carotid arteries.
We present the case of a 44-year-old Caucasian man who was admitted with complaints of loin pain and hypertension. A computed tomography scan of the abdomen revealed a right renal infarction with a nodular aspect of the right renal artery. Subsequent renal angiography revealed a typical 'string of beads' pattern of the right renal artery with thrombus formation. Oral anticoagulation was started and the secondary hypertension was easily controlled with anti-hypertensive drugs. At follow-up, our patient refused percutaneous transluminal renal angioplasty as a definitive treatment.
Fibromuscular dysplasia is the most common cause of renovascular hypertension in patients under 50 years of age. Presentation with renal infarction is rare.In fibromuscular dysplasia, angioplasty has been proven to have, at least for some indications, an advantage over anti-hypertensive drugs. Therefore, hypertension secondary to fibromuscular dysplasia is the most common cause of curable hypertension.
纤维肌发育异常是一种非动脉粥样硬化、非炎症性疾病,最常累及肾动脉和颈内动脉。
我们报告一例44岁的白人男性,因腰痛和高血压入院。腹部计算机断层扫描显示右肾梗死,右肾动脉呈结节状。随后的肾血管造影显示右肾动脉典型的“串珠样”改变并伴有血栓形成。开始口服抗凝治疗,继发性高血压很容易用抗高血压药物控制。在随访中,我们的患者拒绝接受经皮腔内肾血管成形术作为确定性治疗。
纤维肌发育异常是50岁以下患者肾血管性高血压最常见的原因。以肾梗死为表现较为罕见。在纤维肌发育异常中,血管成形术已被证明至少在某些适应症方面优于抗高血压药物。因此,纤维肌发育异常继发的高血压是可治愈高血压最常见的原因。