Prins Bernhardlaan 6, NL-2628 BW Delft, The Netherlands.
Lab Chip. 2010 Oct 7;10(19):2513-8. doi: 10.1039/c002625e. Epub 2010 Jul 9.
We present a closed-form expression that allows the reader to predict the size of bubbles and droplets created in T-junctions without fitting. Despite the wide use of microfluidic devices to create bubbles and droplets, a physically sound expression for the size of bubbles and droplets, key in many applications, did not yet exist. The theoretical foundation of our expression comprises three main ingredients: continuity, geometrics and recently gained understanding of the mechanism which leads to pinch-off. Our simple theoretical model explains why the size of bubbles and droplets strongly depends on the shape of a T-junction, and teaches how the shape can be tuned to obtain the desired size. We successfully validated our model experimentally by analyzing the formation of gas bubbles, as well as liquid droplets, in T-junctions with a wide variety of shapes under conditions typical to multiphase microfluidics.
我们提出了一个封闭形式的表达式,读者无需拟合即可预测 T 型分叉中生成的气泡和液滴的大小。尽管微流控设备被广泛用于制造气泡和液滴,但在许多应用中,对于气泡和液滴大小的物理合理表达式尚不存在。我们的表达式的理论基础包括三个主要成分:连续性、几何形状以及最近对导致断裂的机制的理解。我们的简单理论模型解释了为什么气泡和液滴的大小强烈取决于 T 型分叉的形状,以及如何调整形状以获得所需的大小。我们通过分析在典型多相微流控条件下具有各种形状的 T 型分叉中气体气泡以及液体液滴的形成,成功地通过实验验证了我们的模型。