Lancashire Care NHS Trust Early Intervention Service, The Mount, Whalley Road, Accrington BB5 5DE, United-Kingdom.
Eur Psychiatry. 2010 Jun;25 Suppl 2:S37-40. doi: 10.1016/S0924-9338(10)71705-3.
This international meeting discussed the management of physical health in patients with schizophrenia in several countries including France, Spain, Germany, the UK and Italy. Physical health parameters, including weight, blood pressure, blood glucose, lipids and standard biochemical assessments are measured in many patients at the first hospital consultation. These reveal physical disorders such as obesity, hypertension, dyslipidaemia, the metabolic syndrome, substance abuse, cardiovascular disease, extrapyramidal symptoms, sexual dysfunction and diabetes in substantial proportions of patients. Psychiatrists consider switching antipsychotic therapy if excessive sedation, extrapyramidal symptoms, unacceptable weight gain, hyperglycaemia or dyslipidaemia occur. In general, switching is more likely to be considered for symptomatic adverse events than for laboratory abnormalities. Switching is discouraged by limited knowledge of protocols, the absence of guidelines and fears of relapse or reduced treatment adherence. The physical health of patients with schizophrenia receives much less attention in the community setting than in the hospital setting. Improved guidelines, protocols, resources and support are needed to improve the physical health of patients in the community.
本次国际会议讨论了法国、西班牙、德国、英国和意大利等国家的精神分裂症患者的身体健康管理问题。在许多患者的首次就诊时,都会测量体重、血压、血糖、血脂和标准生化评估等身体健康参数。这些参数揭示了大量患者存在肥胖、高血压、血脂异常、代谢综合征、物质滥用、心血管疾病、锥体外系症状、性功能障碍和糖尿病等身体紊乱问题。如果出现过度镇静、锥体外系症状、无法接受的体重增加、高血糖或血脂异常等情况,精神科医生会考虑更换抗精神病药物治疗。一般来说,对于症状性不良反应,比对于实验室异常,更有可能考虑换药。由于对方案的了解有限、缺乏指南以及担心复发或治疗依从性降低,换药会受到阻碍。社区环境中精神分裂症患者的身体健康问题得到的关注远不及医院环境中多。需要改进指南、方案、资源和支持,以改善社区患者的身体健康。