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孕妇多发性骨髓瘤的麻醉管理。

Anaesthetic management of a pregnant patient with multiple myeloma.

机构信息

Department of Anaesthesia and Intensive Care, West Middlesex University Hospital, London, UK.

出版信息

Int J Obstet Anesth. 2010 Jul;19(3):336-9. doi: 10.1016/j.ijoa.2010.03.010.

Abstract

We describe a 42-year-old multiparous woman who was admitted to our hospital in the 28 th week of her twin pregnancy because of anaemia and proteinuria. She was subsequently diagnosed with multiple myeloma. An uncomplicated elective caesarean section was performed at 35 weeks under combined spinal-epidural anaesthesia with a good outcome for mother and both babies. After two weeks, however, the mother developed cardiac failure due to peripartum cardiomyopathy. To our knowledge, there have been no more then twenty reports of multiple myeloma in pregnant patients, of which only five have been diagnosed during pregnancy. This is the first case report describing anaesthetic implications and management of a parturient with multiple myeloma.

摘要

我们描述了一位 42 岁的多产妇,她在双胎妊娠的第 28 周因贫血和蛋白尿而入院。随后她被诊断为多发性骨髓瘤。在 35 周时,她在脊髓-硬膜外联合麻醉下进行了一次无并发症的择期剖宫产,母婴均预后良好。然而,两周后,母亲因围产期心肌病发生心力衰竭。据我们所知,妊娠患者中多发性骨髓瘤的报告不到二十例,其中只有五例在妊娠期间确诊。这是首例描述多发性骨髓瘤产妇的麻醉影响和管理的病例报告。

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