青霉素结合蛋白2对大肠杆菌ponB菌株生长细胞的完整性至关重要。
Penicillin-binding protein 2 is essential for the integrity of growing cells of Escherichia coli ponB strains.
作者信息
García del Portillo F, de Pedro M A
机构信息
Centro de Biología Molecular, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain.
出版信息
J Bacteriol. 1991 Jul;173(14):4530-2. doi: 10.1128/jb.173.14.4530-4532.1991.
Abstract
Analysis of Escherichia coli pbpA(Ts) or rodA(Ts) strains defective for penicillin-binding protein (PBP) 1A or PBP 1B indicated that the activity of PBP 2 is essential to prevent cell lysis in PBP 1B(-) strains and suggested that PBP 2 is active or activatable in rodA(Ts) mutants under restrictive conditions.
摘要
对青霉素结合蛋白（PBP）1A或PBP 1B存在缺陷的大肠杆菌pbpA（Ts）或rodA（Ts）菌株的分析表明，PBP 2的活性对于防止PBP 1B（-）菌株中的细胞裂解至关重要，并且表明在限制条件下，PBP 2在rodA（Ts）突变体中具有活性或可被激活。
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