Ushikoshi S, Hida K, Kikuchi Y, Iwasaki Y, Miyasaka K, Abe H
Department of Radiology and Neurosurgery, Hokkaido University School of Medicine; Sapporo, Japan -
Interv Neuroradiol. 2000 Nov 30;6 Suppl 1(Suppl 1):203-7. doi: 10.1177/15910199000060S133. Epub 2001 May 15.
We retrospectively reviewed our treatment results for spinal intramedullary arteriovenous malformations (AVMs). Fifteen consecutive patients were included in this syudy. Five patient underwent particulate embolization. Surgery was performed in ten patients (including two patient who were treated embolization initially). Five patients, at the beginning of our experience, underwent radical excision of the nidus via the posterior myelotomy. Recent five patients underwent interruption of the feeding pedicles on the surface of the spinal cord. Especially when arteriovenous fistulas (AVFs) or aneurysms were demonstrated, accurate obliteration of them were performed. Four patients, including two with residual AVM after the surgery, underwent irradiation therapy. Anatomically, four AVMs disappeared completely and the other 11 patients have a residual lesions after the treatment. Clinically, three patients improved, six remained unchanged, and six worsened. The causes of neurological deterioration after the treatment were technical complication of embolization in one patient and surgical manipulation in five. There was no patient who experienced hemorrhage during the followup period ranged from 6 months to 17 years, with a mean of 7.5 years. In conclusion, particulate embolization should be considered as the first choice of treatment if feasible. Surgical treatment is indicated for the dangerous anatomical features such as AVFs or aneurysms.
我们回顾性分析了脊髓髓内动静脉畸形(AVM)的治疗结果。本研究纳入了连续的15例患者。5例患者接受了颗粒栓塞治疗。10例患者接受了手术治疗(其中包括2例最初接受栓塞治疗的患者)。在我们经验初期,5例患者通过后路脊髓切开术对畸形病灶进行了根治性切除。最近的5例患者接受了脊髓表面供血蒂的阻断术。特别是当发现动静脉瘘(AVF)或动脉瘤时,对其进行了精确闭塞。4例患者,包括2例术后有残留AVM的患者,接受了放射治疗。从解剖学角度来看,4例AVM完全消失,其他11例患者治疗后有残留病灶。临床上,3例患者病情改善,6例无变化,6例病情恶化。治疗后神经功能恶化的原因,1例是栓塞技术并发症,5例是手术操作。在6个月至17年(平均7.5年)的随访期内,无患者发生出血。总之,可行的话,颗粒栓塞应被视为首选治疗方法。对于具有如AVF或动脉瘤等危险解剖特征的患者,应进行手术治疗。