Dept. of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Psychiatry Res. 2011 Feb 28;185(3):459-61. doi: 10.1016/j.psychres.2010.07.007. Epub 2010 Jul 31.
In a study of 471 bipolar disorder (BD) cases and 1761 controls, individuals with BD were 6.8 times more likely to report a lifetime history of cannabis use. Rates of DSM-IV cannabis use disorders in those with BD were 29.4% and were independently and significantly associated with increased suicide attempts, greater likelihood of mixed episodes and greater disability attributable to BD.
在一项对 471 例双相情感障碍(BD)病例和 1761 例对照的研究中,BD 患者报告终生使用大麻的可能性是对照组的 6.8 倍。BD 患者中 DSM-IV 大麻使用障碍的发生率为 29.4%,且与自杀未遂增加、混合发作的可能性更大以及归因于 BD 的残疾程度更高独立且显著相关。