Jawalekar S, Surve V T, Bhutey A K
Department of Biochemistry, M. G. M. Medical College, Kamothe, Navi Mumbai, India.
Nepal Med Coll J. 2010 Mar;12(1):5-7.
From the analysis of various urinary constituents and the estimation of serum parameters, it is now possible to identify the risk factors responsible for or contributing for stone formation metabolic factor included calcium, oxalate, uric acid, citrate and pH. Environmental factors where total volume, sodium, phosphate and magnesium. Urinary citrate and magnesium found to be lower in stone formers. The levels of serum parameters like calcium, sodium and intact parathyroid hormone (IPTH) is higher than normal. Where as potassium and magnesium is found to be lower than normal. Higher level of IPTH is associated with primary hyperparathyroidism and is related with stone formation in-patient with urolithiasis. Serum levels of phosphorus, uric acid and Creatinine found to be normal.
通过对各种尿液成分的分析和血清参数的评估,现在有可能确定导致结石形成或促成结石形成的风险因素,代谢因素包括钙、草酸盐、尿酸、柠檬酸盐和pH值。环境因素包括总体积、钠、磷酸盐和镁。结石形成者的尿柠檬酸盐和镁含量较低。血清参数如钙、钠和完整甲状旁腺激素(IPTH)水平高于正常。而钾和镁低于正常水平。较高水平的IPTH与原发性甲状旁腺功能亢进有关,并且与尿路结石患者的结石形成有关。血清磷、尿酸和肌酐水平正常。