Department of Gynecology, Cancer Institute Hospital, Tokyo, Japan.
Int J Gynecol Cancer. 2010 Aug;20(6):1025-30. doi: 10.1111/IGC.0b013e3181e598bb.
Introduced in 1992, the Shimodaira-Taniguchi conization procedure addresses the disadvantages of the loop electrosurgical excision procedure by relying on a high frequency current of 150 W and a triangular probe with a 0.25-mm linear excision electrode to extract a single informative specimen. We conducted a retrospective study to evaluate Shimodaira-Taniguchi conization as a conservative therapy for cervical intraepithelial neoplasia (CIN) and microinvasive cancer of the cervix.
Subjects were 455 patients who underwent Shimodaira-Taniguchi conization for CIN, carcinoma in situ, adenocarcinoma in situ, or stage IA microinvasive cervical carcinoma at our hospital from January 2005 to December 2008. Patient follow-up ranged from 13 to 60 months. Clinical data were obtained and evaluated.
Mean operation time was 11 minutes, and average blood loss was 9.9 mL. Margins were positive in 178 (39.1%) cases. Postsurgical complications occurred in 61 patients, with secondary hemorrhage occurring in 46 patients. None required transfusion. None were lost to follow-up, and there was no disease-related death. Disease recurred in 6 (1.3%) patients: 4 with a positive excision margin and 2 with a negative margin. Cervical stenosis occurred in 15 (3.3%) patients, 3 of whom suffered cervical obstruction, including 1 with dysmenorrhea who underwent hysterectomy. In most cases (n = 357, 78%), a single adequate specimen was extracted.
As a conservative treatment for CIN and microinvasive cervical cancer, Shimodaira-Taniguchi conization is useful. It is easy, provides adequate histologic specimens (often singular), and results in few postoperative complications.
1992 年引入的 Shimodaira-Taniguchi 锥切术通过使用 150 W 的高频电流和带有 0.25-mm 线性切除电极的三角形探头来解决环电切术的缺点,从而提取单个有信息的标本。我们进行了一项回顾性研究,以评估 Shimodaira-Taniguchi 锥切术作为治疗宫颈上皮内瘤变(CIN)和宫颈微浸润癌的保守疗法。
2005 年 1 月至 2008 年 12 月,我院共对 455 例 CIN、原位癌、原位腺癌或 IA 期微浸润宫颈癌患者行 Shimodaira-Taniguchi 锥切术。患者随访时间为 13 至 60 个月。获取并评估临床资料。
平均手术时间为 11 分钟,平均出血量为 9.9 毫升。178 例(39.1%)边缘阳性。61 例患者发生术后并发症,其中 46 例发生继发性出血。无一例需要输血。无失访病例,无与疾病相关的死亡。6 例(1.3%)患者疾病复发:4 例切缘阳性,2 例切缘阴性。15 例(3.3%)发生宫颈狭窄,其中 3 例宫颈梗阻,包括 1 例痛经行子宫切除术。在大多数情况下(n = 357,78%),提取了单个足够的标本。
Shimodaira-Taniguchi 锥切术作为 CIN 和宫颈微浸润癌的保守治疗方法是有用的。它操作简单,提供足够的组织学标本(通常为单个标本),且术后并发症少。