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兔体内有和没有羟基磷灰石涂层的激光改性钛植入物的表面和生物力学研究

Surface and biomechanical study of titanium implants modified by laser with and without hydroxyapatite coating, in rabbits.

作者信息

Sisti Karin E, de Rossi Rafael, Antoniolli Andreia M Brochado, Aydos Ricardo D, Guastaldi Antonio C, Queiroz Thallita P, Garcia Idelmo R, Piattelli Adriano, Tavares Hewerson S

机构信息

Federal University of Mato Grosso do Sul, UFMS, Campo Grande, Brazil.

出版信息

J Oral Implantol. 2012 Jun;38(3):231-7. doi: 10.1563/AAID-JOI-D-10-00030. Epub 2010 Aug 6.

Abstract

Surface and biomechanical analysis of titanium implant surfaces modified by laser beam with and without hydroxyapatite. Titanium implants with 3 different surfaces were inserted into the tibias of 30 rabbits: group I (GI) machined surface (control group), group II irradiated with laser (GII), and group III irradiated with laser and hydroxyapatite coating applied-biomimetic method (GIII). Topographical analysis with scanning electron microscopy was made before surgery in the tibia. These rabbits were distributed into 2 periods of observation: 4 and 8 weeks postsurgery, after which biomechanical analysis (removal torque) was conducted. Statistical analysis used the Student-Newman-Keuls method. Surface showed roughness in GII and GIII. Biomechanical analysis demonstrated values with significant differences in GII and GIII. Titanium implants modified by laser irradiation can increase osseointegration during the initial phase.

摘要

有和没有羟基磷灰石的激光束改性钛种植体表面及生物力学分析。将具有3种不同表面的钛种植体植入30只兔子的胫骨中:第一组(GI)为机械加工表面(对照组),第二组用激光照射(GII),第三组用激光照射并采用仿生方法施加羟基磷灰石涂层(GIII)。在胫骨手术前用扫描电子显微镜进行形貌分析。这些兔子被分为2个观察期:术后4周和8周,之后进行生物力学分析(去除扭矩)。统计分析采用Student-Newman-Keuls方法。GII组和GIII组表面显示出粗糙度。生物力学分析表明GII组和GIII组的值有显著差异。激光照射改性的钛种植体在初始阶段可增加骨整合。

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