Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Eur J Vasc Endovasc Surg. 2010 Oct;40(4):443-9. doi: 10.1016/j.ejvs.2010.07.008. Epub 2010 Aug 5.
With advancements in transplantation and improved long-term allograft survival, the once rare clinical scenario of an abdominal aortic aneurysm (AAA) in a patient with a functioning allograft has become much more frequent. In transplant recipients, AAA repair has the potential to cause irreversible ischaemic injury to the transplanted organ. Different case series and case reports have mentioned a variety of techniques to offer protection to the transplanted organs during aneurysm repair such as cold perfusion, shunting, temporary surgical bypass and extracorporeal circuits etc. Critical review of these adjuncts seems to suggest that that they do not give any better results than just using a "clamp and go" approach. Endovascular aneurysm repair (EVAR) may offer some advantages for transplant patients who have suitable anatomy for endovascular stent deployment. In addition to these surgical techniques, various aspects of medical management for renal, cardiac and hepatic transplant recipients undergoing AAA repair are discussed.
随着移植技术的进步和长期同种异体移植物存活率的提高,曾经在临床中罕见的移植后患者发生腹主动脉瘤(AAA)的情况变得更加常见。在移植受者中,AAA 修复有可能对移植器官造成不可逆转的缺血损伤。不同的病例系列和病例报告提到了多种技术,可在动脉瘤修复期间为移植器官提供保护,例如低温灌注、分流、临时手术旁路和体外循环等。对这些辅助手段的严格审查表明,它们并不比“夹闭并进行”的方法效果更好。对于具有适合血管内支架放置的解剖结构的移植患者,血管内动脉瘤修复(EVAR)可能提供一些优势。除了这些手术技术外,还讨论了接受 AAA 修复的肾、心和肝移植受者在医学管理方面的各个方面。