头颈部癌放化疗后吞咽困难的针刺疗法：病例系列报告。
Acupuncture for dysphagia after chemoradiation therapy in head and neck cancer: a case series report.
机构信息
Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.
出版信息
Integr Cancer Ther. 2010 Sep;9(3):284-90. doi: 10.1177/1534735410378856. Epub 2010 Aug 16.
BACKGROUND
Dysphagia is a common side effect following chemoradiation therapy (CRT) in patients with head and neck cancer (HNC).
METHODS
In this retrospective case series, 10 patients with HNC were treated with acupuncture for radiation-induced dysphagia and xerostomia. All patients were diagnosed with stage III/IV squamous cell carcinoma. In all, 7 of 10 patients were percutaneous endoscopic gastrostomy (PEG) tube dependent when they began acupuncture. Manual acupuncture and electroacupuncture were used once a week.
RESULTS
A total of 9 of 10 patients reported various degrees of subjective improvement in swallowing functions, xerostomia, pain, and fatigue levels. Overall, 6 (86%) of 7 PEG tube-dependent patients had their feeding tubes removed after acupuncture, with a median duration of 114 days (range 49 to 368 days) post CRT. One typical case is described in detail.
CONCLUSIONS
A relatively short PEG tube duration and reduced symptom severity following CRT were observed in these patients. Formal clinical trials are required to determine the causality of the observations.
背景
头颈部癌症（HNC）患者在接受放化疗（CRT）后常出现吞咽困难。
方法
在这项回顾性病例系列研究中，10 名 HNC 患者接受了针刺治疗放疗引起的吞咽困难和口干。所有患者均被诊断为 III/IV 期鳞状细胞癌。在开始针刺时，共有 7 名患者依赖经皮内镜胃造口术（PEG）管。每周进行一次手动针刺和电针治疗。
结果
10 名患者中有 9 名报告了吞咽功能、口干、疼痛和疲劳程度的不同程度的主观改善。总的来说，在针刺治疗后，7 名依赖 PEG 管的患者中有 6 名（86%）拔掉了喂养管，中位时间为 CRT 后 114 天（范围为 49 至 368 天）。详细描述了一个典型病例。
结论
这些患者的 PEG 管持续时间相对较短，CRT 后症状严重程度降低。需要进行正式的临床试验来确定观察结果的因果关系。
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