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[有助于合理使用抗菌药物的微生物检测系统及抗菌谱]

[Microorganism test systems and antibiograms useful for the proper use of antibacterial agents].

作者信息

Takahashi Shunji

机构信息

Department of Clinical Laboratory, Sapporo City General Hospital, Sapporo 060-8604, Japan.

出版信息

Rinsho Byori. 2010 Jul;58(7):711-4.

Abstract

Antimicrobial agents are used for the accurate diagnosis of infectious diseases and effective implementation of antibacterial chemotherapy. The role of microbiological technologists is to provide data from microorganism tests useful for rapid infection treatment. Gram strain can be used to observe microorganisms and neutrophils from specimens of a patient. It is also possible to estimate the kinds of microorganism. If bacterial infectious disease is negative, there is no need for antibacterial chemotherapy. The applied dose of antibacterial agents is different in every hospital. Also, there is a difference in the percentage antibacterial agent susceptibility of isolates. Antibiograms must be created to investigate local factors. For empiric therapy, antibiograms are useful when choosing antibacterial agents showing marked efficacy against the clinical isolate. Microorganism test systems which are useful for the proper use of antibacterial agents are necessary to facilitate safe antibacterial chemotherapy and prevent the development of resistant bacteria. We report a microorganism test system employed at the Sapporo City General Hospital.

摘要

抗菌 agents are used for the accurate diagnosis of infectious diseases and effective implementation of antibacterial chemotherapy. The role of microbiological technologists is to provide data from microorganism tests useful for rapid infection treatment. Gram strain can be used to observe microorganisms and neutrophils from specimens of a patient. It is also possible to estimate the kinds of microorganism. If bacterial infectious disease is negative, there is no need for antibacterial chemotherapy. The applied dose of antibacterial agents is different in every hospital. Also, there is a difference in the percentage antibacterial agent susceptibility of isolates. Antibiograms must be created to investigate local factors. For empiric therapy, antibiograms are useful when choosing antibacterial agents showing marked efficacy against the clinical isolate. Microorganism test systems which are useful for the proper use of antibacterial agents are necessary to facilitate safe antibacterial chemotherapy and prevent the development of resistant bacteria. We report a microorganism test system employed at the Sapporo City General Hospital.

抗菌药物用于传染病的准确诊断和抗菌化疗的有效实施。微生物技术人员的作用是提供来自微生物检测的数据,这些数据有助于快速治疗感染。革兰氏染色可用于观察患者标本中的微生物和中性粒细胞。还可以估计微生物的种类。如果细菌感染性疾病检测结果为阴性,则无需进行抗菌化疗。每家医院使用的抗菌药物剂量不同。此外,分离株对抗菌药物的敏感率也存在差异。必须创建抗菌谱来调查当地因素。对于经验性治疗,在选择对临床分离株显示出显著疗效的抗菌药物时,抗菌谱很有用。有助于正确使用抗菌药物的微生物检测系统对于促进安全的抗菌化疗和防止耐药菌的产生是必要的。我们报告了札幌市立综合医院采用的一种微生物检测系统。

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