Department of Biochemistry, University of Allahabad, Allahabad, India.
Oxid Med Cell Longev. 2010 Jan-Feb;3(1):2-12. doi: 10.4161/oxim.3.1.10476.
Aging is an inevitable universal biological process, which can be characterized by a general decline in physiological function with the accumulation of diverse adverse changes and increased probability of death. Among several theories, oxidative stress/free radical theory offers the best mechanistic elucidation of the aging process and other age -related phenomenon. In the present paper , we discuss the aging process and have focused on the importance of some reliable markers of oxidative stress which may be used as biomarkers of the aging process.
衰老是一种不可避免的普遍生物学过程,可以概括为随着各种不利变化的积累和死亡概率的增加,生理功能的普遍下降。在几种理论中,氧化应激/自由基理论为衰老过程和其他与年龄相关的现象提供了最好的机制解释。在本文中,我们讨论了衰老过程,并重点讨论了一些可靠的氧化应激标志物的重要性,这些标志物可用作衰老过程的生物标志物。