法国引入肺炎球菌结合疫苗前后复杂性急性中耳炎的微生物进化。
Evolving microbiology of complicated acute otitis media before and after introduction of the pneumococcal conjugate vaccine in France.
机构信息
Service de Microbiologie, Hôpital Robert Debré (AP-HP), Paris, Université Denis-Diderot-Paris7, France.
出版信息
Diagn Microbiol Infect Dis. 2010 Sep;68(1):89-92. doi: 10.1016/j.diagmicrobio.2010.04.012.
We compare the microbiology of otopathogens causing recurrent acute otitis media (AOM) or AOM treatment failure in 600 children during 2000 to 2008 before and after the introduction of 7-valent pneumococcal conjugate vaccine (PCV-7). Streptococcus pneumoniae predominated before PCV-7 introduction and during 2007 to 2008, whereas Haemophilus influenzae predominated during 2005 to 2006. S. pneumoniae 19A became the most frequent serotype after PCV-7 introduction.
我们比较了 2000 年至 2008 年期间 600 名患有复发性急性中耳炎（AOM）或 AOM 治疗失败的儿童的耳病原体的微生物学，在此之前和之后引入了 7 价肺炎球菌结合疫苗（PCV-7）。在 PCV-7 引入之前和 2007 年至 2008 年期间，肺炎链球菌占主导地位，而在 2005 年至 2006 年期间，流感嗜血杆菌占主导地位。PCV-7 引入后，19A 型肺炎球菌成为最常见的血清型。
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