Cardiothoracic Division, Liverpool Heart and Chest NHS Foundation Trust, Liverpool, United Kingdom.
Ann Thorac Surg. 2010 Sep;90(3):996-7. doi: 10.1016/j.athoracsur.2010.02.103.
Wegener's granulomatosis is an autoimmune condition resulting in the granulomatous vasculitis of small-to-medium-sized vessels, and is characterized by granulomatous lesions in the renal and respiratory systems. Cardiac involvement in Wegener's granulomatosis has been previously reported. However, involvement of cardiac valves is extremely rare. We present a patient with Wegener's granulomatosis with an extensive mitral mass extending to the aortic valve.
韦格纳肉芽肿病是一种自身免疫性疾病,导致小至中等大小血管的肉芽肿性血管炎,其特征是在肾脏和呼吸系统中出现肉芽肿性病变。韦格纳肉芽肿病的心脏受累先前已有报道。然而,心脏瓣膜受累极为罕见。我们报告了一例韦格纳肉芽肿病患者,其二尖瓣广泛受累,延伸至主动脉瓣。