Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.
Br J Surg. 2010 Oct;97(10):1518-27. doi: 10.1002/bjs.7152.
A proportion of patients do not recover fully from surgery or they develop chronic postsurgical pain. The aim of this study was to examine the incidence and predictors of unfavourable long-term outcome after surgery using a prospective cohort design.
Some 401 patients undergoing various elective surgical procedures filled in the RAND 36-item Health Survey 1.0 health-related quality-of-life questionnaire before operation and at 6 and 12 months of follow-up to assess changes in pain, physical functioning, mental health and vitality. Preoperative psychological assessment was obtained.
Most patients showed improvement in the various aspects of health-related quality of life after surgery, but a considerable proportion (14-24 per cent) still showed deterioration at 6 and 12 months. Multivariable linear regression analysis identified acute postoperative pain, duration of the operation and preoperative physical condition as the most important predictors of long-term pain and physical functioning. Preoperative surgical fear also had a small but significant contribution. The main predictors of mental health and vitality were physical condition before surgery, surgical fear and optimism.
Up to a quarter of patients experienced suboptimal recovery after surgery. Both somatic and psychological factors were associated with the long-term outcome. Optimal recovery could be promoted by effective interventions on malleable factors.
一部分患者在手术后无法完全康复,或出现慢性术后疼痛。本研究旨在采用前瞻性队列设计,调查手术患者不良长期预后的发生率和预测因素。
401 例接受各种择期手术的患者在术前、术后 6 个月和 12 个月时填写 RAND 36 项健康调查 1.0 健康相关生活质量问卷,以评估疼痛、身体机能、心理健康和活力的变化。同时获得术前心理评估。
大多数患者在手术后健康相关生活质量的各个方面都有所改善,但仍有相当一部分(14%-24%)在术后 6 个月和 12 个月时出现恶化。多变量线性回归分析确定急性术后疼痛、手术持续时间和术前身体状况是长期疼痛和身体机能的最重要预测因素。术前手术恐惧也有较小但显著的贡献。心理健康和活力的主要预测因素是术前身体状况、手术恐惧和乐观程度。
多达四分之一的患者在手术后恢复不佳。躯体和心理因素均与长期预后相关。通过对可改变因素的有效干预,可以促进最佳康复。