同步作为注意力增益调制的一种机制。
Synchronization as a mechanism for attentional gain modulation.
作者信息
Tiesinga Paul H E, Fellous Jean-Marc, Salinas Emilio, José Jorge V, Sejnowski Terrence J
机构信息
Department of Physics & Astronomy, University of North Carolina at Chapel Hill, 184 Phillips Hall, Chapel Hill, NC 27599, USA.
出版信息
Neurocomputing (Amst). 2004 Jun 1;58-60:641-646. doi: 10.1016/j.neucom.2004.01.108.
Responses of neurons in monkey visual cortex are modulated when attention is directed into the receptive field of the neuron: the gain or sensitivity of the response is increased or the synchronization of the spikes to the local field potential (LFP) is increased. We investigated, using model simulations, whether the synchrony of inhibitory networks could link these observations. We found that, indeed, an increase in inhibitory synchrony could enhance the coherence of the model neurons with the simulated LFP, and could have different effects on the firing rate. When the firing rate vs. current (f-I) response curves saturated at high I, attention yielded a shift in sensitivity; alternatively, when the f-I curves were non-saturating, the most significant effect was on the gain of the response. This suggests that attention may act through changes in the synchrony of inhibitory networks.
当注意力指向猴子视觉皮层中神经元的感受野时，该神经元的反应会受到调制：反应的增益或敏感性增加，或者动作电位与局部场电位（LFP）的同步性增加。我们使用模型模拟来研究抑制性网络的同步性是否能将这些观察结果联系起来。我们发现，实际上，抑制性同步性的增加可以增强模型神经元与模拟LFP的相干性，并且对放电率有不同的影响。当放电率与电流（f-I）反应曲线在高电流时饱和时，注意力会导致敏感性发生变化；或者，当f-I曲线不饱和时，最显著的影响是对反应增益的影响。这表明注意力可能通过抑制性网络同步性的变化起作用。
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