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对34例多胎妊娠进行胚胎减灭术后的产科结局

Obstetrical results after embryonic reductions performed on 34 multiple pregnancies.

作者信息

Boulot P, Hedon B, Pelliccia G, Deschamps F, Benos P, Audibert F, Arnal F, Humeau C, Mares P, Laffargue F

机构信息

Department of Obstetrics and Gynaecology, Montpellier-Nimes University of Medicine, France.

出版信息

Hum Reprod. 1990 Nov;5(8):1009-13. doi: 10.1093/oxfordjournals.humrep.a137207.

Abstract

Thirty-four women with multiple pregnancies (three or more fetuses) underwent embryonic reduction in order to reduce abortions, premature births or fetal growth-retardation by obtention of twins. Four early abortions occurred. Thirty pregnancies reached term and out of 60 fetuses, 58 infants were born alive. Fetal death in utero of one twin occurred in two pregnancies. The mean term until delivery was 36 +/- 2.8 weeks gestation and the prematurity rate was 51.7%. Of 55 neonates, 25 were underweight within the 10th percentile and 10 out of 55 neonates were underweight below the 3rd percentile. There were three deaths in the early neonatal period. The rate of perinatal mortality was 8.3%. Fifty-four children are currently healthy and one child has a mild axial hypotonia. A reduction in prematurity was observed with a gain of 2 weeks on reported data concerning triplet pregnancies. The rate of low-birth-weight infants was high, 63.5% being underweight at birth.

摘要

34名怀有多胎妊娠(三胎或更多胎儿)的女性接受了胚胎减灭术,目的是通过获得双胎妊娠来减少流产、早产或胎儿生长受限。发生了4例早期流产。30例妊娠足月,60个胎儿中,58名婴儿存活出生。2例妊娠中发生了1例双胎之一的宫内胎儿死亡。分娩的平均孕周为36±2.8周,早产率为51.7%。55名新生儿中,25名体重低于第10百分位数,55名新生儿中有10名体重低于第3百分位数。早期新生儿期有3例死亡。围产期死亡率为8.3%。目前54名儿童健康,1名儿童有轻度轴性肌张力减退。与报道的三胎妊娠数据相比,观察到早产有所减少,孕周增加了2周。低出生体重婴儿的比例很高,63.5%的婴儿出生时体重不足。

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