Endo Masahiro, Mori Shinichiro, Kandatsu Susumu, Tanada Shuji, Kondo Chisato
Department of Planning and Management, National Institute of Radiological Sciences, Inage-ku, Chiba, Japan.
Radiol Phys Technol. 2008 Jan;1(1):20-6. doi: 10.1007/s12194-007-0004-z. Epub 2007 Nov 1.
Since our initial development of the 256-detector row CT scanner (256-row CT) for four-dimensional (4D) imaging of moving organs in 2003, the results of physical performance and those in animal and human studies have suggested that this scanner may be useful in the examination of moving organs such as the heart and lungs. We have now developed a second model of the 256-row CT with improved specifications, with a scan time of 0.5 s/rotation at the highest speed and real-time reconstruction and display of dynamic 3D images (4D images). Here, we investigated the image characteristics of the new model, including spatial resolution, noise, and low-contrast detectability, as well as the dose profile and its integral in stationary phantoms. One volunteer and one patient with lung cancer were scanned, and their images were evaluated. The results show that all characteristics have been improved compared with those of the first model, with a remarkable improvement in the low-contrast detectability and slice sensitivity profile. In a contrast study, coronary arteries were clearly visualized in the normal heart without electrocardiographic gating. Movement and deformation of the tumor in the patient with lung cancer was captured in a study of a single breath cycle. The second model 256-row CT with improved characteristics may be beneficial in imaging of moving organs such as the heart and lungs, and may enable cerebral perfusion studies of the whole brain.
自2003年我们最初开发用于对运动器官进行四维(4D)成像的256排探测器CT扫描仪(256排CT)以来,其物理性能结果以及动物和人体研究结果均表明,该扫描仪可能有助于对心脏和肺等运动器官进行检查。我们现已开发出具有改进规格的第二代256排CT,其最高速度下的扫描时间为0.5秒/旋转,并能实时重建和显示动态3D图像(4D图像)。在此,我们研究了新模型的图像特征,包括空间分辨率、噪声和低对比度可探测性,以及在静态体模中的剂量分布及其积分。对一名志愿者和一名肺癌患者进行了扫描,并对他们的图像进行了评估。结果表明,与第一代模型相比,所有特征均有所改善,低对比度可探测性和切片敏感性分布有显著提高。在一项对比研究中,在没有心电图门控的情况下,正常心脏中的冠状动脉清晰可见。在对一名肺癌患者的单次呼吸周期研究中,捕捉到了肿瘤的运动和变形。具有改进特征的第二代256排CT可能有助于对心脏和肺等运动器官进行成像,并可能实现全脑的脑灌注研究。