八条目 Morisky 用药依从性量表（MMAS）：马来西亚版的翻译与验证。
The eight-item Morisky Medication Adherence Scale MMAS: translation and validation of the Malaysian version.
机构信息
School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.
出版信息
Diabetes Res Clin Pract. 2010 Nov;90(2):216-21. doi: 10.1016/j.diabres.2010.08.012. Epub 2010 Sep 15.
AIMS
To translate and examine the psychometric properties of the Malaysian version of the Morisky Medication Adherence Scale (MMAS) among patients with type 2 diabetes.
METHODS
A standard "forward-backward" procedure was used to translate MMAS into Malay language. It was later validated on a convenience sample of 223 type 2 diabetes outpatients between May and September 2009. Reliability was tested for internal consistency. Validity was confirmed using convergent and known group validity.
RESULTS
Employing the recommended scoring method, the mean±SD of MMAS scores was 6.13±1.72. Moderate internal consistency was found (Cronbach's α=0.675), the test-retest reliability value was 0.816 (p<0.001). A positive correlation between the eight- and four-item MMAS was found (r=0.792; p<0.01). A significant relationship between MMAS categories and HbA1c categories (χ(2)=20.261; p≥0.001) was found. The MMAS sensitivity and specificity, with positive and negative predictive values were 77.61%, 45.37%, 46.84% and 76.56%, respectively.
CONCLUSIONS
The findings of this validation study indicate that the Malaysian version of the MMAS is a reliable and valid measure of medication adherence which can now be used.
目的
将 Morisky 药物依从性量表（MMAS）的马来版本翻译并检验其在 2 型糖尿病患者中的心理计量特性。
方法
采用标准的“前后”翻译程序将 MMAS 翻译成马来语。随后在 2009 年 5 月至 9 月间对 223 名 2 型糖尿病门诊患者进行了验证。采用内部一致性测试评估了信度。采用聚合效度和已知组有效性进行了效度确认。
结果
采用推荐的评分方法，MMAS 评分的平均值±标准差为 6.13±1.72。发现具有中度的内部一致性（Cronbach's α=0.675），重测信度值为 0.816（p<0.001）。发现八条目和四条目 MMAS 之间存在正相关（r=0.792；p<0.01）。还发现 MMAS 类别与 HbA1c 类别之间存在显著关系（χ(2)=20.261；p≥0.001）。MMAS 的灵敏度和特异性，以及阳性和阴性预测值分别为 77.61%、45.37%、46.84%和 76.56%。
结论
本验证研究的结果表明，马来语版的 MMAS 是一种可靠且有效的药物依从性测量工具，现在可以使用。
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