Department of Medicine, Queen Elizabeth Foundation Hospital Trust, Gateshead.
Clin Med (Lond). 2010 Aug;10(4):326-9. doi: 10.7861/clinmedicine.10-4-326.
Morbidity and mortality from pneumonia is increased in patients with rheumatoid arthritis. Factors contributing to this have been recently identified and a number of recommendations have been implemented in an attempt to reverse this trend. The present paper shows that these measures have combined to produce a fourfold reduction in both admissions and case fatality rates. In the study population, immunisation rates against influenza and pneumococcus have improved to 86% and 65%, oral steroid consumption has halved and disease modifying drugs were usually appropriately suspended during acute infection. These measures may now merit more widespread adoption.
类风湿关节炎患者的肺炎发病率和死亡率增加。最近已经确定了导致这种情况的因素,并提出了一些建议,试图扭转这一趋势。本文表明,这些措施共同作用,使住院率和病死率均降低了四分之三。在研究人群中,流感和肺炎球菌的疫苗接种率分别提高到了 86%和 65%,口服类固醇的使用量减少了一半,在急性感染期间,疾病修正药物通常会适当暂停使用。这些措施现在可能值得更广泛地采用。