超声弹性成像在临床定量评估脂肪肝中的应用。
Ultrasonic elastography in clinical quantitative assessment of fatty liver.
机构信息
Department of Ultrasonic Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
出版信息
World J Gastroenterol. 2010 Oct 7;16(37):4733-7. doi: 10.3748/wjg.v16.i37.4733.
AIM
To investigate the clinical application of ultrasonic elastography in quantitative assessment of fatty liver grading.
METHODS
A total of 105 patients with fatty liver were divided into mild group (n = 46), moderate group (n = 39), and severe group (n = 20). Forty-five healthy individuals served as a normal control group. All patients who underwent routine ultrasound scan and further ultrasonic elastography were evaluated accordingly to the evaluation standards for ultrasonic elastography. The ratio of surface areas of blue region/total surface area in the desired region was measured.
RESULTS
Ultrasonic elastography technique, in comparison to traditional ultrasound, had a rather high consistence in grading of fatty liver [κ value = (95.3%-63.6%)/(1%-63.6%) = 0.87, P = 0.001]. The score of ultrasonic elastography increased with the severity of fatty liver with a sensitivity of 97.14% and a specificity of 91.11%. A significant difference was found in the ratio of surface areas of blue regions between different groups (P < 0.05).
CONCLUSION
Ultrasonic elastography can be used in quantitative assessment of the severity of fatty liver.
目的
探讨超声弹性成像在定量评估脂肪肝分级中的临床应用。
方法
将 105 例脂肪肝患者分为轻度组（n=46）、中度组（n=39）和重度组（n=20），另选取 45 例健康者作为正常对照组。所有患者均行常规超声扫查及进一步超声弹性成像检查，根据超声弹性成像评分标准进行评估，测量感兴趣区域内蓝色区域面积与总面积的比值。
结果
超声弹性成像技术与传统超声在脂肪肝分级方面具有较高的一致性[κ 值=（95.3%-63.6%）/（1%-63.6%）=0.87，P=0.001]。超声弹性成像评分随脂肪肝严重程度增加而升高，其灵敏度为 97.14%，特异度为 91.11%。不同组间蓝色区域面积比值比较，差异有统计学意义（P<0.05）。
结论
超声弹性成像可用于定量评估脂肪肝的严重程度。
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