Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Ophthalmology. 2011 Mar;118(3):581-5. doi: 10.1016/j.ophtha.2010.07.017. Epub 2010 Sep 29.
To report refractive and surgical outcomes in a cohort of children with accommodative esotropia.
Retrospective population-based cohort.
All pediatric patients (<19 years) diagnosed with accommodative esotropia in Olmsted County, Minnesota, from January 1, 1975, to December 31, 1994.
Medical records identified by the Rochester Epidemiology Project were reviewed for spectacle and surgical management.
Rate of surgical intervention and discontinuation of spectacles for esotropia.
A total of 306 children with accommodative esotropia were diagnosed during the study years; 244 (80%) had fully accommodative esotropia (FAET) and 62 (20%) had partially accommodative esotropia (PAET). The Kaplan-Meier rate of discontinuing spectacles for strabismus in this population was 8% by 5 years after diagnosis, 20% by 10 years, and 37% by 20 years. Children born prematurely (P = 0.046) or with a greater initial hyperopic refractive error (P<0.001) were significantly less likely to become spectacle-free during the follow-up period. During a median follow-up of 9.8 years (range, 0-27.9 years), 33 (13.5%) of the 244 subjects with FAET eventually underwent strabismus surgery. Male gender (P = 0.039) and an earlier age at onset (P = 0.008) and diagnosis (P<0.001) of FAET were associated with a higher likelihood of requiring surgery.
The majority of children with accommodative esotropia in this population continued to require spectacle correction into their second decade of life. A small proportion of children with FAET required surgical intervention, which was more likely to occur among boys and in those with an earlier age at onset and diagnosis of their deviation.
报告适应型内斜视患儿的屈光和手术结果。
回顾性基于人群的队列研究。
1975 年 1 月 1 日至 1994 年 12 月 31 日,明尼苏达州奥姆斯特德县诊断为适应型内斜视的所有儿科患者(<19 岁)。
通过罗切斯特流行病学项目确定的病历回顾了眼镜和手术管理情况。
手术干预和斜视停戴眼镜的比例。
研究期间共诊断出 306 例适应型内斜视儿童;244 例(80%)为完全适应型内斜视(FAET),62 例(20%)为部分适应型内斜视(PAET)。在该人群中,斜视停戴眼镜的 Kaplan-Meier 率在诊断后 5 年为 8%,10 年为 20%,20 年为 37%。早产儿(P=0.046)或初始远视屈光不正较大的儿童(P<0.001)在随访期间明显不太可能成为无需戴镜者。在中位数为 9.8 年(范围,0-27.9 年)的随访期间,244 例 FAET 中有 33 例最终接受了斜视手术。男性(P=0.039)、FAET 发病年龄较早(P=0.008)和诊断较早(P<0.001)与更有可能需要手术相关。
该人群中大多数适应型内斜视患儿在其二十几岁时仍需戴眼镜矫正。一小部分 FAET 患儿需要手术干预,男孩和 FAET 发病年龄和诊断年龄较早的患儿更有可能需要手术干预。