[针灸对干眼症泪液分泌的疗效评估]

[Efficacy assessment of acupuncture and moxibustion on tear secretion in xerophthalmia].

作者信息

Wei Li-Xin, Yang Wei, Wang Hong-Cai, Zhang Ou, Ding Rui-Qing, Liu Zhao-Hui

机构信息

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhen Jiu. 2010 Sep;30(9):709-12.

PMID:20886787

Abstract

OBJECTIVE

To compare the efficacy differences between acupuncture-moxibustion and medication in xerophthalmia.

METHODS

Eighty cases of xerophthalmia were randomly divided into an acupuncture-moxibustion group and a medication group, 40 cases in each group. In acupuncture-moxibustion group, acupuncture was applied to the local and distal points, such as Jingming (BL 1), Cuanzhu (BL 2), Taiyang (EX-HN 5) and Quchi (LI 11) etc., combined with non-smoking moxibustion. In medication group, Sodium Hyaluronate eye drops were administered, three times per day, 1 drop each time. Before and after treatment, tear secretion volume (Schirmer's test), break-up time (BUT), symptom score, visual function score and tear film grade were observed.

RESULTS

The total effective rate was 73.1% (57/78) in acupuncture-moxibustion group, and was 37.2% (29/78) in medication group, indicating significant statistical difference in comparison (P < 0.05). There was a significant difference in statistics in tear secretion volume between two groups after treatment (P < 0.05), in which, the result in acupuncture-moxibustion group was superior to that in medication group. The significant statistical differences presented in tear secretion volume, BUT, symptom score, visual function score and tear film grade in comparison before and after treatment in acupuncture-moxibustion group (all P < 0.05). The significant statistical difference presented in symptom score and tear film grade before and after treatment in medication group (both P < 0.05).

CONCLUSION

Acupuncture-moxibustion apparently relieves the symptoms of xerophthalmia, promotes tear secretion and improves the life quality of patients.

摘要

目的

比较针灸与药物治疗干眼症的疗效差异。

方法

将80例干眼症患者随机分为针灸组和药物组，每组40例。针灸组选取局部及远端穴位如睛明（BL 1）、攒竹（BL 2）、太阳（EX-HN 5）、曲池（LI 11）等进行针刺，并结合无烟艾灸。药物组给予透明质酸钠滴眼液滴眼，每日3次，每次1滴。观察治疗前后泪液分泌量（Schirmer试验）、泪膜破裂时间（BUT）、症状评分、视功能评分及泪膜分级。

结果

针灸组总有效率为73.1%（57/78），药物组为37.2%（29/78），两组比较差异有统计学意义（P < 0.05）。治疗后两组泪液分泌量比较差异有统计学意义（P < 0.05），针灸组优于药物组。针灸组治疗前后泪液分泌量、BUT、症状评分、视功能评分及泪膜分级比较差异均有统计学意义（均P < 0.05）。药物组治疗前后症状评分及泪膜分级比较差异有统计学意义（均P < 0.05）。