Gårdhagen Roland, Lantz Jonas, Carlsson Fredrik, Karlsson Matts
Department of Management and Engineering and Center for Medical Image Science and Visualization (CMIV), Linköping University, SE-581 83 Linköping, Sweden.
J Biomech Eng. 2010 Jun;132(6):061002. doi: 10.1115/1.4001075.
Large eddy simulation was applied for flow of Re=2000 in a stenosed pipe in order to undertake a thorough investigation of the wall shear stress (WSS) in turbulent flow. A decomposition of the WSS into time averaged and fluctuating components is proposed. It was concluded that a scale resolving technique is required to completely describe the WSS pattern in a subject specific vessel model, since the poststenotic region was dominated by large axial and circumferential fluctuations. Three poststenotic regions of different WSS characteristics were identified. The recirculation zone was subject to a time averaged WSS in the retrograde direction and large fluctuations. After reattachment there was an antegrade shear and smaller fluctuations than in the recirculation zone. At the reattachment the fluctuations were the largest, but no direction dominated over time. Due to symmetry the circumferential time average was always zero. Thus, in a blood vessel, the axial fluctuations would affect endothelial cells in a stretched state, whereas the circumferential fluctuations would act in a relaxed direction.
为了深入研究湍流中的壁面剪应力(WSS),对狭窄管道中雷诺数Re = 2000的流动进行了大涡模拟。提出了将WSS分解为时间平均分量和脉动分量的方法。得出的结论是,由于狭窄后区域主要由大的轴向和周向脉动主导,因此需要一种尺度解析技术来完整描述特定个体血管模型中的WSS模式。识别出了具有不同WSS特征的三个狭窄后区域。再循环区域受到逆行方向的时间平均WSS和大幅脉动的影响。重新附着后,存在顺行剪应力且脉动比再循环区域小。在重新附着处,脉动最大,但随时间没有占主导的方向。由于对称性,周向时间平均值始终为零。因此,在血管中,轴向脉动会影响处于拉伸状态的内皮细胞,而周向脉动会沿松弛方向起作用。