美国成年人代谢综合征流行率持续上升：NHANES III 至 NHANES 1999-2006。
Persistent increase of prevalence of metabolic syndrome among U.S. adults: NHANES III to NHANES 1999-2006.
机构信息
Department of Health, Nutrition and Exercise Sciences, North Dakota State University, Fargo, North Dakota, USA.
出版信息
Diabetes Care. 2011 Jan;34(1):216-9. doi: 10.2337/dc10-0879. Epub 2010 Oct 1.
OBJECTIVE
To compare the prevalence in metabolic syndrome (MetSyn) between 1988-1994 and 1999-2006 among U.S. adults of different races or ethnicities.
RESEARCH DESIGN AND METHODS
Analysis of data on 6,423 adult men and nonpregnant women aged ≥20 years from Third National Health and Nutrition Examination Survey (NHANES III) and 6,962 participants from the combined NHANES 1999-2006 were done. The revised National Cholesterol Education Program Adult Treatment Panel III definition was used to calculate MetSyn.
RESULTS
Both the unadjusted prevalence (27.9 ± 1.1% to 34.1 ± 0.8%, P < 0.001) and age-adjusted prevalence (29.2 ± 1.0% to 34.2 ± 0.7%, P < 0.001) increased from NHANES III to NHANES 1999-2006, respectively. Although MetSyn prevalence was highest in Mexican Americans, significant increases in prevalence occurred among non-Hispanic whites and non-Hispanic blacks, especially among younger women.
CONCLUSIONS
The persistent increase of MetSyn among U.S. adults is a serious public health concern because it raises the likelihood of increased prevalence of type 2 diabetes.
目的
比较美国不同种族或族裔成年人在 1988-1994 年和 1999-2006 年之间代谢综合征（MetSyn）的患病率。
研究设计和方法
对第三次全国健康和营养检查调查（NHANES III）中≥20 岁的 6423 名成年男性和非孕妇以及合并的 NHANES 1999-2006 中的 6962 名参与者的数据进行分析。采用修订后的国家胆固醇教育计划成人治疗专家组 III 定义计算 MetSyn。
结果
未经调整的患病率（27.9±1.1%至 34.1±0.8%，P<0.001）和年龄调整的患病率（29.2±1.0%至 34.2±0.7%，P<0.001）分别从 NHANES III 增加到 NHANES 1999-2006。尽管墨西哥裔美国人的 MetSyn 患病率最高，但非西班牙裔白人和非西班牙裔黑人群体的患病率显著增加，尤其是年轻女性。
结论
美国成年人代谢综合征患病率的持续增加是一个严重的公共卫生问题，因为这增加了 2 型糖尿病患病率增加的可能性。
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