Depp Colin A, Mausbach Brent, Granholm Eric, Cardenas Veronica, Ben-Zeev Dror, Patterson Thomas L, Lebowitz Barry D, Jeste Dilip V
Department of Psychiatry, University of California, San Diego, CA, USA.
J Nerv Ment Dis. 2010 Oct;198(10):715-21. doi: 10.1097/NMD.0b013e3181f49ea3.
Mobile devices can be used to deliver psychosocial interventions, yet there is little prior application in severe mental illness. We provide the rationale, design, and preliminary data from 3 ongoing clinical trials of mobile interventions developed for bipolar disorder or schizophrenia. Project 1 used a personal digital assistant to prompt engagement in personalized self-management behaviors based on real-time data. Project 2 employed experience sampling through text messages to facilitate case management. Project 3 was built on group functional skills training for schizophrenia by incorporating between-session mobile phone contacts with therapists. Preliminary findings were of minimal participant attrition, and no broken devices; yet, several operational and technical barriers needed to be addressed. Adherence was similar to that reported in nonpsychiatric populations, with high participant satisfaction. Therefore, mobile devices seem feasible and acceptable in augmenting psychosocial interventions for severe mental illness, with future research in establishing efficacy, cost effectiveness, and ethical and safety protocols.
移动设备可用于提供心理社会干预措施,但此前在严重精神疾病方面的应用较少。我们提供了为双相情感障碍或精神分裂症开发的3项正在进行的移动干预临床试验的基本原理、设计和初步数据。项目1使用个人数字助理,根据实时数据促使患者参与个性化自我管理行为。项目2通过短信进行经验抽样,以促进病例管理。项目3基于针对精神分裂症的团体功能技能训练,通过在疗程之间加入与治疗师的手机联系来开展。初步研究结果显示参与者流失极少,且没有设备损坏;然而,一些操作和技术障碍仍需解决。依从性与非精神病患者群体报告的情况相似,参与者满意度较高。因此,移动设备在增强针对严重精神疾病的心理社会干预方面似乎是可行且可接受的,未来还需开展研究以确定其疗效、成本效益以及伦理和安全协议。