Department of Clinical Oncology, University of Hong Kong, Hong Kong SAR, China.
Int J Radiat Oncol Biol Phys. 2011 May 1;80(1):291-300. doi: 10.1016/j.ijrobp.2010.06.014.
To compare the image quality and dosimetry on the Varian cone beam computed tomography (CBCT) system between software Version 1.4.13 and Version 1.4.11 (referred to as "new" and "old" protocols, respectively, in the following text). This study investigated organ absorbed dose, total effective dose, and image quality of the CBCT system for the head-and-neck and pelvic regions.
A calibrated Farmer chamber and two standard cylindrical Perspex CT dosimetry phantoms with diameter of 16 cm (head phantom) and 32 cm (body phantom) were used to measure the weighted cone-beam computed tomography dose index (CBCTDIw) of the Varian CBCT system. The absorbed dose of different organs was measured in a female anthropomorphic phantom with thermoluminescent dosimeters (TLD) and the total effective dose was estimated according to International Commission on Radiological Protection (ICRP) Publication 103. The dose measurement and image quality were studied for head-and-neck and pelvic regions, and comparison was made between the new and old protocols.
The values of the new CBCTDIw head-and-neck and pelvic protocols were 36.6 and 29.4 mGy, respectively. The total effective doses from the new head-and-neck and pelvic protocols were 1.7 and 8.2 mSv, respectively. The absorbed doses of lens for the new 200° and old 360° head-and-neck protocols were 3.8 and 59.4 mGy, respectively. The additional secondary cancer risk from daily CBCT might be up to 2.8%.
The new Varian CBCT provided volumetric information for image guidance with acceptable image quality and lower radiation dose. This imaging tool gave a better standard for patient daily setup verification.
比较瓦里安锥形束 CT(CBCT)系统在软件版本 1.4.13 和 1.4.11 之间的图像质量和剂量学(在下文分别称为“新”和“旧”协议)。本研究调查了头颈部和盆腔区域 CBCT 系统的器官吸收剂量、总有效剂量和图像质量。
使用校准的 Farmer 室和两个直径为 16cm(头部体模)和 32cm(体部体模)的标准圆柱形 Perspex CT 剂量体模来测量瓦里安 CBCT 系统的加权锥形束 CT 剂量指数(CBCTDIw)。使用热释光剂量计(TLD)测量不同器官在女性人体模型中的吸收剂量,并根据国际辐射防护委员会(ICRP)第 103 号出版物估算总有效剂量。对头颈部和盆腔区域进行剂量测量和图像质量研究,并比较新旧协议。
新的 CBCTDIw 头颈部和盆腔协议的数值分别为 36.6 和 29.4mGy。新的头颈部和盆腔协议的总有效剂量分别为 1.7 和 8.2mSv。新的 200°和旧的 360°头颈部协议的晶状体吸收剂量分别为 3.8 和 59.4mGy。每日 CBCT 可能会增加 2.8%的继发癌症风险。
新的瓦里安 CBCT 提供了容积信息以进行图像引导,具有可接受的图像质量和较低的辐射剂量。这种成像工具为患者每日设置验证提供了更好的标准。