Department of Epidemiology, Michigan State University, East Lansing, MI 48824, USA.
Stroke. 2010 Dec;41(12):2924-31. doi: 10.1161/STROKEAHA.110.598664. Epub 2010 Oct 21.
Quality of care may be influenced by patient and hospital factors. Our goal was to use multilevel modeling to identify patient-level and hospital-level determinants of the quality of acute stroke care in a stroke registry.
During 2001 to 2002, data were collected for 4897 ischemic stroke and TIA admissions at 96 hospitals from 4 prototypes of the Paul Coverdell National Acute Stroke Registry. Duration of data collection varied between prototypes (range, 2-6 months). Compliance with 8 performance measures (recombinant tissue plasminogen activator treatment, antithrombotics < 24 hours, deep venous thrombosis prophylaxis, lipid testing, dysphagia screening, discharge antithrombotics, discharge anticoagulants, smoking cessation) was summarized in a composite opportunity score defined as the proportion of all needed care given. Multilevel linear regression analyses with hospital specified as a random effect were conducted.
The average hospital composite score was 0.627. Hospitals accounted for a significant amount of variability (intraclass correlation = 0.18). Bed size was the only significant hospital-level variable; the mean composite score was 11% lower in small hospitals (≤ 145 beds) compared with large hospitals (≥ 500 beds). Significant patient-level variables included age, race, ambulatory status documentation, and neurologist involvement. However, these factors explained < 2.0% of the variability in care at the patient level.
Multilevel modeling of registry data can help identify the relative importance of hospital-level and patient-level factors. Hospital-level factors accounted for 18% of total variation in the quality of care. Although the majority of variability in care occurred at the patient level, the model was able to explain only a small proportion.
医疗质量可能受到患者和医院因素的影响。我们的目标是使用多水平模型,从患者层面和医院层面确定卒中登记处急性卒中护理质量的决定因素。
在 2001 年至 2002 年期间,从 Paul Coverdell 国家急性卒中登记处的 4 个原型中,在 96 家医院收集了 4897 例缺血性卒中和 TIA 入院患者的数据。数据收集的持续时间在不同原型之间有所不同(范围为 2-6 个月)。将 8 项绩效指标(重组组织型纤溶酶原激活剂治疗、抗血栓药物<24 小时、深静脉血栓预防、血脂检测、吞咽困难筛查、出院抗血栓药物、出院抗凝药物、戒烟)的依从性总结为一个综合机会评分,定义为给予所有需要的护理的比例。采用以医院为随机效应的多水平线性回归分析。
平均医院综合评分 0.627。医院占了很大的变异量(组内相关系数=0.18)。床位数是唯一显著的医院层面变量;与大医院(≥500 床)相比,小医院(≤145 床)的平均综合评分低 11%。显著的患者层面变量包括年龄、种族、活动状态记录和神经科医生参与。然而,这些因素仅解释了护理质量在患者层面的<2.0%的变异。
对登记处数据进行多水平建模可以帮助确定医院层面和患者层面因素的相对重要性。医院层面因素占护理质量总变异的 18%。尽管护理的大部分变异发生在患者层面,但该模型只能解释很小的一部分。