Iwamoto Jun, Matsumoto Hideo, Takeda Tsuyoshi, Sato Yoshihiro, Uzawa Mitsuyoshi
Institute for Integrated Sports Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
J Osteoporos. 2010;2010:748380. doi: 10.4061/2010/748380. Epub 2009 Dec 20.
The purpose of the present study was to determine the associations of age and history of non- and low-traumatic fractures with the severity of abdominal aortic calcification in Japanese postmenopausal women and men. Four hundred and one Japanese persons (24 men and 377 postmenopausal women, mean age: 73.8 years) for whom thoracic and lumbar spine radiographs had been obtained to evaluate their posture prior to patient participation in a fall-prevention exercise program were enrolled. The associations of sex, age, history of hip fracture, prevalence of vertebral fracture, and spondylosis grade (the Nathan degree) with the severity of abdominal aortic calcification (length of calcification, as evaluated according to the number of vertebral bodies) were analyzed. Nine subjects (2.2%) had a history of hip fracture, and 221 (55.1%) had at least one prevalent vertebral fracture. Two hundred and sixty-seven subjects (66.6%) had first-degree spondylosis. Age and the number of prevalent vertebral fractures, but not sex, history of hip fracture, or spondylosis grade, were significantly associated with the severity of abdominal aortic calcification. The present study confirmed that age and the number of vertebral fractures were associated with the severity of abdominal aortic calcification in Japanese postmenopausal women and men.
本研究的目的是确定年龄以及非创伤性和低创伤性骨折史与日本绝经后女性和男性腹主动脉钙化严重程度之间的关联。招募了401名日本人(24名男性和377名绝经后女性,平均年龄:73.8岁),这些人在参与预防跌倒运动项目之前已进行了胸腰椎X光检查以评估其姿势。分析了性别、年龄、髋部骨折史、椎体骨折患病率和脊柱病分级(内森分级)与腹主动脉钙化严重程度(钙化长度,根据椎体数量评估)之间的关联。9名受试者(2.2%)有髋部骨折史,221名(55.1%)至少有一处椎体骨折。267名受试者(66.6%)有一级脊柱病。年龄和椎体骨折的数量与腹主动脉钙化严重程度显著相关,而性别、髋部骨折史或脊柱病分级则不然。本研究证实,年龄和椎体骨折数量与日本绝经后女性和男性腹主动脉钙化严重程度相关。