应对儿童和青少年自闭症谱系障碍中的易怒和攻击行为。
Managing irritability and aggression in autism spectrum disorders in children and adolescents.
作者信息
Robb Adelaide S
机构信息
Department of Psychiatry and Pediatrics, George Washington University Medical Center, Children's National Medical Center, Washington, DC, USA.
出版信息
Dev Disabil Res Rev. 2010;16(3):258-64. doi: 10.1002/ddrr.118.
Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] J. Autism Dev. Disord. 36:1101-1114.). These symptoms can lead to impairment and distress in both home and school settings. Medications to treat the irritability will be discussed across categories of antipsychotics, antidepressants, antihypertensive agents, and others. Emphasis will be placed on medications with the most safety and efficacy and FDA approval.
患有自闭症和自闭症谱系障碍的儿童出现易怒和攻击性行为症状的比例很高。在一项研究中，高达20%的自闭症儿童有易怒和攻击性行为症状，包括攻击、严重发脾气和故意自伤行为（勒卡瓦利尔[2006年]《自闭症与发育障碍杂志》36:1101 - 1114）。这些症状会导致家庭和学校环境中的功能受损和困扰。将讨论用于治疗易怒症状的各类药物，包括抗精神病药、抗抑郁药、抗高血压药等。重点将放在安全性和疗效最高且获得美国食品药品监督管理局批准的药物上。
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