Yared Kibar, Lam Kaitlyn My-Tu, Hung Judy
Department of Medicine, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Curr Cardiol Rev. 2009 Nov;5(4):312-22. doi: 10.2174/157340309789317841.
Mitral regurgitation (MR) is the second most common valvular disease in western countries after aortic stenosis. Optimal management of patients with MR depends on the etiology of the regurgitation and is based predominantly on left ventricular function and functional status. Recent outcome studies report high risk subsets of asymptomatic patients with MR, and practice guidelines underscore the importance of a well-established estimation of exercise tolerance and recommend exercise testing to objectively assess functional status and hemodynamic factors.
二尖瓣反流(MR)是西方国家仅次于主动脉瓣狭窄的第二常见瓣膜疾病。二尖瓣反流患者的最佳管理取决于反流的病因,主要基于左心室功能和功能状态。最近的结局研究报告了无症状二尖瓣反流患者的高风险亚组,实践指南强调了准确评估运动耐量的重要性,并建议进行运动测试以客观评估功能状态和血流动力学因素。