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[上颈椎结核(3例报告并文献复习)]

[Pott's disease of the upper cervical spine (three cases and literature review)].

作者信息

Bouabdellah Mohamed, Bouzidi Ramzi, Kammoun Skander, Mohamed Fredj, Amara Karim, Chaabouni Lilia, Kooli Mondher, Zlitni Mongi

机构信息

Service d'orthopédie traumatologie, Hôpital Charles Nicolle Tunis.

出版信息

Tunis Med. 2010 Nov;88(11):847-50.

Abstract

BACKGROUND

Sub-occipital Pott's disease is rare, but dangerous.

AIM

To recall diagnostic aspects and spatially the neuroradiological ones of sub-occipital Pott's disease.

METHODS

We describe three patients with sub-occipital Pott's disease followed in our department from 2002 to 2007.

RESULTS

There were two women and one man (mean age at onset: 48 years). The early clinical picture was non specific. Exploration, in addition to standard radiographies included a computerized Tomography (CT) (n=2) and MRI (n=1 and n=3). The diagnosis was confirmed histologically on a biopsy of the abscess (n=1), a bacteriological evidence (n=2) and retained thanks to argument presumption (n=3). The treatment was based on quadruple antituberculous chemotherapy with external traction (n=2 and n=3) associated with urgent surgery (n=1) because of the worsening of the neurological complications. The evolution was fatal (n=1) and positive (n=2 and n=3).

CONCLUSION

Tuberculosis should be suspected in patients with chronic torticollis and residing in an area when tuberculosis is endemic. Medical treatment is based on a quadruple antituberculosis chemotherapy with traction in the presence of atlanto-axial instability. Surgery is reserved in case of neurological worsening or persistent instability.

摘要

背景

枕下结核性脊椎炎罕见但危险。

目的

回顾枕下结核性脊椎炎的诊断要点及神经放射学特征。

方法

我们描述了2002年至2007年在我科诊治的3例枕下结核性脊椎炎患者。

结果

2例女性,1例男性(发病时平均年龄48岁)。早期临床表现不具特异性。检查除标准X线片外,还包括计算机断层扫描(CT)(2例)和磁共振成像(MRI)(1例和3例)。通过脓肿活检组织学确诊(1例)、细菌学证据确诊(2例)以及根据推测确诊(3例)。治疗基于四联抗结核化疗并辅以外部牵引(2例和3例),1例因神经并发症恶化而接受紧急手术。转归为1例死亡,2例和3例好转。

结论

对于患有慢性斜颈且居住在结核病流行地区的患者应怀疑患有结核病。药物治疗基于四联抗结核化疗并在存在寰枢椎不稳时进行牵引。若出现神经功能恶化或持续不稳则需进行手术。

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