Istanbul University, Oncology Institute, Department of Medical Radiophysics, Topkapı, Turkey.
Phys Med. 2011 Oct;27(4):203-8. doi: 10.1016/j.ejmp.2010.10.007. Epub 2010 Nov 4.
Beam characteristics of a linear accelerator are of great importance for intensity-modulated radiation therapy (IMRT) to ensure precise and accurate dose delivery to patients. In step-and-shoot IMRT, each beam is delivered through a series of small, segmented fields at low monitor unit (MU) settings. In this study, the beam characteristics of both static (ST) and segmental intensity-modulated (IM) beams were investigated at various dose rates for 6 and 18 MV at low MU settings. Dose linearity was investigated for both the ST and the IM beams. For the ST beams, standard 10 × 10 cm(2) fields were irradiated with MU values ranging from 1 to 100. For the IM beams, 10 × 10 cm(2) and 15 × 15 cm(2) fields were used as subfields. The normalized dose (ND)/MU was obtained. Beam flatness and symmetry for 2 and 10 MU was measured by in-plane (G-T) and cross-plane (R-L) profiles using Kodak XV films. The largest dose/MU discrepancies were observed for 1 MU. For the ST beams, the beam output decreased up to 4.5% for 1 MU at the high dose rates of 6 and 18 MV. Dose variations were less than 1% for doses above 5 MU. No significant variation was observed in the beam profiles of the ST and the IM groups. Beam flatness and symmetry were close to 3% and 2% for 6 and 18 MV, respectively. Our results showed that dose linearity and delivery errors were close to 1% for doses above 5 MU, which is considered acceptable for both 6- and 18-MV ST and IM therapy.
直线加速器的射束特性对于强度调制放射治疗(IMRT)非常重要,以确保向患者精确和准确地输送剂量。在分步照射 IMRT 中,每个射束通过以低监测器单位(MU)设置的一系列小的分段野进行传输。在这项研究中,在低 MU 设置下,研究了 6 和 18 MV 时各种剂量率下静态(ST)和分段强度调制(IM)射束的射束特性。研究了 ST 和 IM 射束的剂量线性度。对于 ST 射束,使用 MU 值范围为 1 至 100 的标准 10×10 cm2 射野进行照射。对于 IM 射束,使用 10×10 cm2 和 15×15 cm2 射野作为子野。获得了归一化剂量(ND)/MU。使用柯达 XV 胶片通过平面内(G-T)和跨平面(R-L)分布测量了 2 和 10 MU 的射束平坦度和对称性。在 1 MU 时观察到最大剂量/MU 差异最大。对于 ST 射束,在高剂量率 6 和 18 MV 时,1 MU 的射束输出下降了 4.5%。在剂量高于 5 MU 时,剂量变化小于 1%。在 ST 和 IM 组的射束分布中未观察到明显的变化。对于 6 和 18 MV,射束平坦度和对称性分别接近 3%和 2%。我们的结果表明,在剂量高于 5 MU 时,剂量线性度和输送误差接近 1%,这对于 6 和 18 MV 的 ST 和 IM 治疗均可以接受。