对 HIV 血清阳性和阴性女性的生殖微生物组进行焦磷酸测序，结果显示，惰性乳杆菌是优势乳杆菌种。
Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals Lactobacillus iners as the predominant Lactobacillus Species.
机构信息
Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.
出版信息
Appl Environ Microbiol. 2011 Jan;77(1):378-81. doi: 10.1128/AEM.00973-10. Epub 2010 Nov 12.
Abstract
The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV(+) women and 90% of HIV(-) women. This has implications for resistance of HIV(+) and HIV(-) women to genital colonization by pathogenic organisms.
摘要
采用 16S 基因焦磷酸测序技术确定 HIV 阳性和阴性妇女的阴道乳杆菌种属。66%的 HIV 阳性妇女和 90%的 HIV 阴性妇女的主要乳杆菌序列为惰性乳杆菌序列。这对 HIV 阳性和 HIV 阴性妇女抵抗致病性生物体生殖定植具有重要意义。
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