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胃近端切除术后空肠袋与空肠间置重建的初步比较研究。

A pilot study comparing jejunal pouch and jejunal interposition reconstruction after proximal gastrectomy.

机构信息

Department of Surgery, Gastroenterological Center, Yokohama City University, Yokohama City University, Graduate School of Medicine, Yokohama, Japan.

出版信息

Dig Surg. 2010;27(6):502-8. doi: 10.1159/000321224. Epub 2010 Nov 16.

Abstract

BACKGROUND/AIMS: The incidence of proximal gastric cancer is increasing, so proximal gastrectomies are often performed to preserve gastric function, but the optimal reconstruction method after surgery remains controversial. We therefore conducted a prospective pilot study comparing reconstructions using jejunal pouch interposition or jejunal interposition.

METHODS

Thirty-eight patients with early proximal gastric cancer were included in this study. Equal numbers of patients were randomly assigned for reconstruction using jejunal interposition (the IP group) or jejunal pouch interposition (the PO group). Postoperative morbidity and patient symptoms were compared between the 2 groups.

RESULTS

Postoperative morbidity was significantly more frequent in the IP than the PO group (p = 0.036). Moreover, the incidence of gastrointestinal complaints was more frequent in the IP group until 6 months after surgery. By contrast, the caloric intake was more favorable in the PO group until 1 year post-surgery.

CONCLUSION

Short-term and mid-term outcomes were more favorable following jejunal pouch interposition compared with jejunal interposition after proximal gastrectomy.

摘要

背景/目的:近端胃癌的发病率正在增加,因此经常进行近端胃切除术以保留胃功能,但手术后的最佳重建方法仍存在争议。因此,我们进行了一项前瞻性试点研究,比较了使用空肠间置术或空肠间置术的重建。

方法

本研究纳入了 38 例早期近端胃癌患者。将患者等分为两组,分别采用空肠间置术(IP 组)或空肠间置术(PO 组)进行重建。比较两组患者术后并发症和患者症状。

结果

IP 组的术后并发症发生率明显高于 PO 组(p = 0.036)。此外,IP 组在术后 6 个月内胃肠道不适的发生率更高。相比之下,PO 组在术后 1 年内的热量摄入更有利。

结论

与近端胃切除术后的空肠间置术相比,空肠间置术具有更好的短期和中期效果。

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